Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis.
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Main roads to melanomaPhosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 bindingEvidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cellsRibosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domainRotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulationRibosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathwayThreshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cellsChemoresistance in human ovarian cancer: the role of apoptotic regulatorsCaloric restriction: is mammalian life extension linked to p53?Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and agingRole of the p53 tumor suppressor in metabolismClinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancerDisruptive chemicals, senescence and immortalityHepatitis C Virus Impairs p53 via Persistent Overexpression of 3 -Hydroxysterol 24-ReductaseThe critical role of Akt in cardiovascular functionPam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complexPharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapyGatifloxacin induces S and G2-phase cell cycle arrest in pancreatic cancer cells via p21/p27/p53MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signalingInvolvement of PTEN in TPA-mediated p53-activation in mouse skin epidermal JB6 cellsProtein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like regionRegulation of the Pro-apoptotic scaffolding protein POSH by Akt.Improving gene set analysis of microarray data by SAM-GS.A novel site of AKT-mediated phosphorylation in the human MDM2 onco-protein.Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival.Role of Nogo-A in neuronal survival in the reperfused ischemic brainInvolvement of miR-605 and miR-34a in the DNA damage response promotes apoptosis induction.Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.Levels of active tyrosine kinase receptor determine the tumor response to ZalypsisPhysiological regulation of Akt activity and stability.AKT and its related molecular feature in aged mice skin.A vicious partnership between AKT and PHLDA3 to facilitate neuroendocrine tumors.A theoretical exploration of birhythmicity in the p53-Mdm2 network.The origins and evolution of the p53 family of genes.A pathway from JNK through decreased ERK and Akt activities for FOXO3a nuclear translocation in response to UV irradiation.Radiosensitization of prostate cancer by priming the wild-type p53-dependent cellular senescence pathway.Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in response to DNA damage.The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons.
P2860
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P2860
Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Cross-talk between Akt, p53 an ...... r the regulation of apoptosis.
@en
type
label
Cross-talk between Akt, p53 an ...... r the regulation of apoptosis.
@en
prefLabel
Cross-talk between Akt, p53 an ...... r the regulation of apoptosis.
@en
P2093
P356
P1433
P1476
Cross-talk between Akt, p53 an ...... r the regulation of apoptosis.
@en
P2093
Juan Fernando Martinez Leal
Moshe Oren
Rony Seger
Tanya M Gottlieb
Yoichi Taya
P2888
P304
P356
10.1038/SJ.ONC.1205181
P407
P577
2002-02-01T00:00:00Z
P5875
P6179
1002286113