Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B.
about
The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta.Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasionSphingosine kinase-1 is cleaved by cathepsin B in vitro: identification of the initial cleavage sites for the proteaseExtracellular alpha 6 integrin cleavage by urokinase-type plasminogen activator in human prostate cancerLysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts.Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner.Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer.Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells.Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironmentCruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion.Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.Cysteine cathepsins in human cancer.Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginaseCathepsin B: multiple roles in cancer.Transforming growth factor β--at the centre of systemic sclerosis.The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence.Matrigel invasion by the prostate cancer cell lines, PC3 and DU145, and cathepsin L+B activity.Cathepsin B: Basis Sequence: Mouse.Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage.Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.Apoptosis of human endothelial cells is accompanied by proteolytic processing of latent TGF-beta binding proteins and activation of TGF-beta.High molecular weight kininogen as substrate for cathepsin B.Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma.
P2860
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P2860
Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Phorbol ester activation of a ...... the exocytosis of cathepsin B.
@en
type
label
Phorbol ester activation of a ...... the exocytosis of cathepsin B.
@en
prefLabel
Phorbol ester activation of a ...... the exocytosis of cathepsin B.
@en
P2093
P2860
P356
P1476
Phorbol ester activation of a ...... the exocytosis of cathepsin B.
@en
P2093
Bonnie F Sloane
Bruce Linebaugh
John J Reiners
Patricia A Mathieu
P2860
P304
14829-14837
P356
10.1074/JBC.M108180200
P407
P577
2002-01-28T00:00:00Z