Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist - Wikidata - awgldk - TriplyDB

Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist

Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist

http://www.wikidata.org/entity/Q40755303

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The Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer´s Disease Marginal Vitamin A Deficiency Exacerbates Memory Deficits Following Aβ1-42 Injection in Rats.A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice Molecular Signaling Mechanisms of Natural and Synthetic Retinoids for Inhibition of Pathogenesis in Alzheimer's Disease.Retinoic acid-elicited RARα/RXRα signaling attenuates Aβ production by directly inhibiting γ-secretase-mediated cleavage of amyloid precursor protein Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury.Retinoic acid as a therapeutic option in Alzheimer's disease: a focus on cholinergic restoration.Selected Micronutrients in Cognitive Decline Prevention and Therapy.Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.Molecular Anti-inflammatory Mechanisms of Retinoids and Carotenoids in Alzheimer's Disease: a Review of Current Evidence.The Vitamin A Derivative All-Trans Retinoic Acid Repairs Amyloid-β-Induced Double-Strand Breaks in Neural Cells and in the Murine Neocortex.Morphogens and blood-brain barrier function in health and disease.Therapeutic potential of nuclear receptor agonists in Alzheimer's disease.Nuclear receptors in neural stem/progenitor cell homeostasis.Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.MicroRNA-138 promotes tau phosphorylation by targeting retinoic acid receptor alpha.Neuronal RARβ Signaling Modulates PTEN Activity Directly in Neurons and via Exosome Transfer in Astrocytes to Prevent Glial Scar Formation and Induce Spinal Cord Regeneration Marginal vitamin A deficiency facilitates Alzheimer's pathogenesis.Age-Related Expression of a Repeat-Rich Intergenic Long Noncoding RNA in the Rat Brain.Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth.All-Trans Retinoic Acid Induces Expression of a Novel Intergenic Long Noncoding RNA in Adult rat Primary Hippocampal Neurons.

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P2860

Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist

http://www.wikidata.org/entity/Q40755303

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Amyloid β inhibits retinoic ac ...... tinoic acid receptor α agonist

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Amyloid β inhibits retinoic ac ...... tinoic acid receptor α agonist

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Amyloid β inhibits retinoic ac ...... tinoic acid receptor α agonist

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European Journal of Neuroscience

P1476

Amyloid β inhibits retinoic ac ...... tinoic acid receptor α agonist

@en

P2093

Carl Hobbs

http://www.w3.org/2001/XMLSchema#string

Earl Clarke

http://www.w3.org/2001/XMLSchema#string

Jonathan P T Corcoran

http://www.w3.org/2001/XMLSchema#string

Julian Jack

http://www.w3.org/2001/XMLSchema#string

Maria B Goncalves

http://www.w3.org/2001/XMLSchema#string

Robert Deacon

http://www.w3.org/2001/XMLSchema#string

Tony Malmqvist

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P2860

The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

ApoE promotes the proteolytic degradation of Abeta

Neuropathological alterations in Alzheimer disease

'Clinical trials in Alzheimer's disease': immunotherapy approaches

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

P304

1182-1192

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scholarly article

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10.1111/EJN.12142

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7

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37

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2013-02-04T00:00:00Z

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235399627

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23379615

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Alzheimer's disease

P932

3655538

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