A high affinity HSF-1 binding site in the 5'-untranslated region of the murine tumor necrosis factor-alpha gene is a transcriptional repressor.
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Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 bindingA novel HSF1-mediated death pathway that is suppressed by heat shock proteinsThe heat shock paradox and cardiac myocytes: role of heat shock factorCXC chemokines: a new family of heat-shock proteins?A novel transcriptional repressor, Rhit, is involved in heat-inducible and age-dependent expression of Mpv17-like protein, a participant in reactive oxygen species metabolism.Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters.The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes.Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis.Tolerogenic dendritic cells that inhibit autoimmune arthritis can be induced by a combination of carvacrol and thermal stress.HSF1 down-regulates XAF1 through transcriptional regulation.Fever and the thermal regulation of immunity: the immune system feels the heat.Epigenetic regulation in alcoholic liver disease.Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits proinflammatory cytokines resulting in endotoxin tolerance.The chaperone balance hypothesis: the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management.Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritisBacterial lipopolysaccharide augments febrile-range hyperthermia-induced heat shock protein 70 expression and extracellular release in human THP1 cellsEarly life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging.Heat shock response and acute lung injury.Heat shock factor 1 protects against lung mycoplasma pneumoniae infection in mice.Shifts in temperature within the physiologic range modify strand-specific expression of select human microRNAsIn the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity.Heat shock transcription factor 1 is activated as a consequence of lymphocyte activation and regulates a major proteostasis network in T cells critical for cell division during stressInhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.Possible Contribution of Zerumbone-Induced Proteo-Stress to Its Anti-Inflammatory Functions via the Activation of Heat Shock Factor 1.Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microgliaImpact of fever-range thermal stress on lymphocyte-endothelial adhesion and lymphocyte trafficking.Toll-like receptor agonists and febrile range hyperthermia synergize to induce heat shock protein 70 expression and extracellular release.Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock.Heat shock proteins and regulatory T cellsRegulation of a lymphocyte-endothelial-IL-6 trans-signaling axis by fever-range thermal stress: hot spot of immune surveillanceHeat-shock factor 1 controls genome-wide acetylation in heat-shocked cellsHeat shock proteins and immunity: application of hyperthermia for immunomodulation.Opposing roles for heat and heat shock proteins in macrophage functions during inflammation: a function of cell activation state?Fever, hyperthermia and the heat shock response.HSF1-mediated regulation of tumor cell apoptosis: a novel target for cancer therapeutics.Fever, immunity, and molecular adaptations.The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes.Functionally significant nicotine acetylcholine receptor subunit α5 promoter haplotypes are associated with susceptibility to lung cancer in Chinese.Multifaceted roles of HSF1 in cancer.
P2860
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P2860
A high affinity HSF-1 binding site in the 5'-untranslated region of the murine tumor necrosis factor-alpha gene is a transcriptional repressor.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
A high affinity HSF-1 binding ...... s a transcriptional repressor.
@en
type
label
A high affinity HSF-1 binding ...... s a transcriptional repressor.
@en
prefLabel
A high affinity HSF-1 binding ...... s a transcriptional repressor.
@en
P2093
P2860
P356
P1476
A high affinity HSF-1 binding ...... s a transcriptional repressor.
@en
P2093
Ishwar S Singh
Jeffrey D Hasday
Stuart Calderwood
P2860
P304
P356
10.1074/JBC.M108154200
P407
P577
2001-12-04T00:00:00Z