A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro.
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Endoglin expression in metastatic breast cancer cells enhances their invasive phenotypeUptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancerGenes that mediate breast cancer metastasis to the brainAnalyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosisBioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient miceRegulation of actin cytoskeleton architecture by Eps8 and Abi1.Doxorubicin-mediated bone loss in breast cancer bone metastases is driven by an interplay between oxidative stress and induction of TGFβEffects of different tissue microenvironments on gene expression in breast cancer cellsAn EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotypeThe vascular basement membrane as "soil" in brain metastasisThe B-Raf status of tumor cells may be a significant determinant of both antitumor and anti-angiogenic effects of pazopanib in xenograft tumor modelsMolecular mechanisms and treatment of bone metastasis.Quantitative T2* imaging of metastatic human breast cancer to brain in the nude rat at 3 TBrain metastases from breast cancer: lessons from experimental magnetic resonance imaging studies and clinical implications.Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model.Up-regulation of bone marrow stromal protein 2 (BST2) in breast cancer with bone metastasis.Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases.ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone.The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival.Plumbagin attenuates cancer cell growth and osteoclast formation in the bone microenvironment of mice.Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis.Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner.Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow.S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling.Identification and analysis of signaling networks potentially involved in breast carcinoma metastasis to the brain.Ultrasound imaging-guided intracardiac injection to develop a mouse model of breast cancer brain metastases followed by longitudinal MRI.A reconstructed metastasis model to recapitulate the metastatic spread in vitro.Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft modelStimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in miceHeterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.Direct but not indirect co-culture with osteogenically differentiated human bone marrow stromal cells increases RANKL/OPG ratio in human breast cancer cells generating bone metastasesBreast cancer metastasis to the central nervous systemThe role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft modelModeling of hypo/hyperglycemia and their impact on breast cancer progression related molecules.Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.Fluoxetine modulates breast cancer metastasis to the brain in a murine modelThe IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells.
P2860
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P2860
A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
A bone-seeking clone exhibits ...... ng clone in vivo and in vitro.
@en
type
label
A bone-seeking clone exhibits ...... ng clone in vivo and in vitro.
@en
prefLabel
A bone-seeking clone exhibits ...... ng clone in vivo and in vitro.
@en
P2093
P1476
A bone-seeking clone exhibits ...... ng clone in vivo and in vitro.
@en
P2093
P304
P356
10.1359/JBMR.2001.16.8.1486
P577
2001-08-01T00:00:00Z