The transmembrane heregulin precursor is functionally active.
about
Transautocrine signaling by membrane neuregulins requires cell surface targeting, which is controlled by multiple domainsBack signaling by the Nrg-1 intracellular domainCombination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells.ErbB4 reduces synaptic GABAA currents independent of its receptor tyrosine kinase activity.An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models.The N-terminal domains of neuregulin 1 confer signal attenuation.Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide.Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.The extracellular linker of pro-neuregulin-alpha2c is required for efficient sorting and juxtacrine function.Exercise training and return to a well-balanced diet activate the neuregulin 1/ErbB pathway in skeletal muscle of obese rats.
P2860
Q35085158-A893A6D3-50A8-45E1-BD4F-BF2091B2727AQ36323571-DC22EF98-E089-422E-9414-373B09589147Q36609570-1FD859CC-BFE4-4331-AC5F-277B40C3E0B4Q37353031-FCD6C48F-6723-462F-8AED-D12D66AE5627Q37690880-F3410A27-E169-441C-AFFE-D11FAB8601CCQ40258125-743F91D7-2E91-4D6A-8BFD-25E1F40FF0B7Q40666006-C9D44E29-1DBA-443B-9661-3EF6BBEA8196Q40687892-F8961115-DC81-4FB2-87D4-7A73FE89E084Q42131728-CBFBD97C-22C9-46A2-92AD-24A7C9BC7ED4Q52955342-03FC83AA-2F8B-4CE1-84EE-2C77D9973FE0
P2860
The transmembrane heregulin precursor is functionally active.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
The transmembrane heregulin precursor is functionally active.
@en
type
label
The transmembrane heregulin precursor is functionally active.
@en
prefLabel
The transmembrane heregulin precursor is functionally active.
@en
P2860
P356
P1476
The transmembrane heregulin precursor is functionally active.
@en
P2093
P2860
P304
44099-44107
P356
10.1074/JBC.M103442200
P407
P577
2001-08-08T00:00:00Z