about
Restricted and conserved T-cell repertoires involved in allorecognition of class II major histocompatibility complex.What is missing in immunology to understand immunity?Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHCUncertainties - discrepancies in immunology.Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.Regulatory T cells for tolerance therapy: revisiting the concept.On 'reactivity' versus 'tolerance'.Evidence for a single-niche model of positive selection.The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex.How many thymocytes audition for selection?On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.Purified hematopoietic stem cell allografts reconstitute immunity superior to bone marrowDissecting the two models of TCR structure-function relationships.Self-reactivity as the necessary cost of maintaining a diverse memory T-cell repertoire.The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.Aberrant expression of tissue-specific proteins in the thymus: a hypothesis for the development of central tolerance.Immunology (1955-1975): the natural selection theory, the two signal hypothesis and positive repertoire selection.CD6: expression during development, apoptosis and selection of human and mouse thymocytes.
P2860
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P2860
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Why positive selection?
@en
type
label
Why positive selection?
@en
prefLabel
Why positive selection?
@en
P2860
P1476
Why positive selection?
@en
P2093
Matzinger P
P2860
P304
P356
10.1111/J.1600-065X.1993.TB00645.X
P577
1993-10-01T00:00:00Z