AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9.
about
P1343
Gelatinase B/MMP-9 in Tumour Pathogenesis and ProgressionIntegrins in the Spotlight of CanceralphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificityIntegrin-mediated regulation of epidermal wound functionsCharacterization of integrin beta6 and thrombospondin-1 double-null miceNMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin αvβ6 ligand specificity.Pathophysiology of fistula formation in Crohn's disease.Cell adhesion molecules and oral cancer.β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition.TGFβ loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion.Role of integrins in regulating epidermal adhesion, growth and differentiation.Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer.Mechanisms of tumour invasion and metastasis: emerging targets for therapy.Structural guided scaffold phage display libraries as a source of bio-therapeutics.Generation and characterization of a diabody targeting the αvβ6 integrin.Role of integrins in regulating proteases to mediate extracellular matrix remodelingA tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation controlAlphavbeta6 integrin in wound healing and cancer of the oral cavity.The alphaVbeta6 integrin as a novel molecular target for colorectal cancer.Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells.Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels.Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis.Defining the role of integrin alphavbeta6 in cancer.Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.The role of integrins in cancer and the development of anti-integrin therapeutic agents for cancer therapy.The role of inflammatory mediators in the development of prostatic hyperplasia and prostate cancerUpregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation.Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cellsIntegrin β6 acts as an unfavorable prognostic indicator and promotes cellular malignant behaviors via ERK-ETS1 pathway in pancreatic ductal adenocarcinoma (PDAC).αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression.Salivary MMP-9 in the detection of oral squamous cell carcinoma.A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo.The role of α9β1 integrin in modulating epithelial cell behaviour.Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion.Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor modelDevelopment of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma.Role for EPS8 in squamous carcinogenesis.Peptide-targeted polyglutamic acid doxorubicin conjugates for the treatment of alpha(v)beta(6)-positive cancers.Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands.
P2860
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P2860
AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
AlphaVbeta6 integrin promotes ...... of matrix metalloproteinase-9.
@en
type
label
AlphaVbeta6 integrin promotes ...... of matrix metalloproteinase-9.
@en
prefLabel
AlphaVbeta6 integrin promotes ...... of matrix metalloproteinase-9.
@en
P2093
P2860
P1476
AlphaVbeta6 integrin promotes ...... of matrix metalloproteinase-9.
@en
P2093
G J Thomas
J F Marshall
P M Speight
P2860
P304
P356
10.1002/1097-0215(20010601)92:5<641::AID-IJC1243>3.0.CO;2-P
P4510
P577
2001-06-01T00:00:00Z