Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by down-regulating its type-II receptor and inducing Smad7.
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GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptorDifferential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skinTransforming growth factor: beta signaling is essential for limb regeneration in axolotlsOxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblastsUltraviolet irradiation represses TGF-β type II receptor transcription through a 38-bp sequence in the proximal promoter in human skin fibroblasts.Transcriptome analysis of skin photoaging in chinese females reveals the involvement of skin homeostasis and metabolic changes.Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis.Retinoids suppress cysteine-rich protein 61 (CCN1), a negative regulator of collagen homeostasis, in skin equivalent cultures and aged human skin in vivo.Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts.Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling.Molecular mechanisms and in vivo mouse models of skin aging associated with dermal matrix alterations.Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skinOxidant exposure induces cysteine-rich protein 61 (CCN1) via c-Jun/AP-1 to reduce collagen expression in human dermal fibroblastsDermal fibroblast expression of stromal cell-derived factor-1 (SDF-1) promotes epidermal keratinocyte proliferation in normal and diseased skin.Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiationRole of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review.Reduction of fibroblast size/mechanical force down-regulates TGF-β type II receptor: implications for human skin aging.Cysteine-rich protein 61 (CCN1) domain-specific stimulation of matrix metalloproteinase-1 expression through αVβ3 integrin in human skin fibroblasts.Photoageing: mechanism, prevention and therapy.Identification of a novel PPARβ/δ/miR-21-3p axis in UV-induced skin inflammation.Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skinMatrix-degrading metalloproteinases in photoaging.The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling.Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts.Smad-induced alterations of matrix metabolism by a myristoyl tetra peptide.Effects of Galla chinensis extracts on UVB-irradiated MMP-1 production in hairless mice.Effects of licarin E on expression of matrix metalloproteinase-1 and type-1 procollagen in UVB-irradiated human skin fibroblasts.Smad7 induces G0/G1 cell cycle arrest in mesenchymal cells by inhibiting the expression of G1 cyclins.2-Methoxyestradiol-induced apoptosis in prostate cancer cells requires Smad7.Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin.Pinus densiflora extract protects human skin fibroblasts against UVB-induced photoaging by inhibiting the expression of MMPs and increasing type I procollagen expression.Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle.Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts.In vitro evaluation of the effects of human umbilical cord extracts on human fibroblasts, keratinocytes, and melanocytes.Differential regulation of transforming growth factor-beta receptors type I and II by platelet-derived growth factor in human dermal fibroblasts.Expression of caveolin-1 in the early phase of beta-TCP implanted in dog mandible.Angelica archangelia Prevented Collagen Degradation by Blocking Production of Matrix Metalloproteinases in UVB-exposed Dermal Fibroblasts.Suggested mechanisms of action of UVA phototherapy in morphea: a molecular study.SMAD7 regulates proinflammatory and prolabor mediators in amnion and myometrium.
P2860
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P2860
Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by down-regulating its type-II receptor and inducing Smad7.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Ultraviolet irradiation blocks ...... I receptor and inducing Smad7.
@en
type
label
Ultraviolet irradiation blocks ...... I receptor and inducing Smad7.
@en
prefLabel
Ultraviolet irradiation blocks ...... I receptor and inducing Smad7.
@en
P2093
P356
P1476
Ultraviolet irradiation blocks ...... I receptor and inducing Smad7.
@en
P2093
P304
26349-26356
P356
10.1074/JBC.M010835200
P407
P577
2001-04-24T00:00:00Z