The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
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Inhibitory effect of bufalin and cinobufagin on steroidogenesis via the activation of ERK in human adrenocortical cellsDetection of hCG responsive expression of the steroidogenic acute regulatory protein in mouse leydig cellsCytoskeleton reorganization mediates alpha6beta1 integrin-associated actions of laminin on proliferation and survival, but not on steroidogenesis of ovine granulosa cellsRole of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial FunctionInsulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycleMolecular basis of bone morphogenetic protein-15 signaling in granulosa cellsACTH-induced nucleocytoplasmic translocation of salt-inducible kinase. Implication in the protein kinase A-activated gene transcription in mouse adrenocortical tumor cellsRegulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cellsActivation of the lutropin/choriogonadotropin receptor in MA-10 cells stimulates tyrosine kinase cascades that activate ras and the extracellular signal regulated kinases (ERK1/2).A mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis.The orphan nuclear receptor NUR77 regulates hormone-induced StAR transcription in Leydig cells through cooperation with Ca2+/calmodulin-dependent protein kinase I.Transactivation of the epidermal growth factor receptor is involved in the lutropin receptor-mediated down-regulation of ovarian aromatase expression in vivo.Mitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondriaDominant negative effects of human follicle-stimulating hormone receptor expression-deficient mutants on wild-type receptor cell surface expression. Rescue of oligomerization-dependent defective receptor expression by using cognate decoys.Novel signaling mechanisms in the ovary during oocyte maturation and ovulation.Ovarian steroids: the good, the bad, and the signals that raise them.A novel mechanism of FSH regulation of DNA synthesis in the granulosa cells of hamster preantral follicles: involvement of a protein kinase C-mediated MAP kinase 3/1 self-activation loopGPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.The role of specific mitogen-activated protein kinase signaling cascades in the regulation of steroidogenesisFollicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphataseInduction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from SmadThe Effect of Cordycepin on Steroidogenesis and Apoptosis in MA-10 Mouse Leydig Tumor Cells.Regulation of luteinizing hormone receptor expression by an RNA binding protein: role of ERK signaling.A delayed gonadotropin-dependent and growth factor-mediated activation of the extracellular signal-regulated kinase 1/2 cascade negatively regulates aromatase expression in granulosa cells.Potential Leydig cell mitogenic signals generated by the wild-type and constitutively active mutants of the lutropin/choriogonadotropin receptor (LHR).Role of the intracellular domains of the human FSH receptor in G(alphaS) protein coupling and receptor expressionCurrent concepts of follicle-stimulating hormone receptor gene regulationStructure, function and regulation of gonadotropin receptors - a perspective.Luteinizing hormone receptor mRNA down-regulation is mediated through ERK-dependent induction of RNA binding protein.C-Peptide reduces mitochondrial superoxide generation by restoring complex I activity in high glucose-exposed renal microvascular endothelial cells.Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.MC-LR Exposure Leads to Subfertility of Female Mice and Induces Oxidative Stress in Granulosa CellsEmbryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.Mutations of the lutropin/choriogonadotropin receptor that do not activate the phosphoinositide cascade allow hCG to induce aromatase expression in immature rat granulosa cellsAromatase expression in the ovary: hormonal and molecular regulation.Gonadotropin stimulation of ovarian fractalkine expression and fractalkine augmentation of progesterone biosynthesis by luteinizing granulosa cells.Molecular mechanisms of ovulation: co-ordination through the cumulus complex.An essential role for the intra-oocyte MAPK activity in the NSN-to-SN transition of germinal vesicle chromatin configuration in porcine oocytes.The luteinizing hormone receptor-activated extracellularly regulated kinase-1/2 cascade stimulates epiregulin release from granulosa cellsArrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells.
P2860
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P2860
The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
@en
type
label
The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
@en
prefLabel
The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
@en
P2093
P2860
P356
P1476
The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
@en
P2093
A Amsterdam
J F Strauss
R Rosenberg
P2860
P304
13957-13964
P356
10.1074/JBC.M006852200
P407
P577
2001-01-22T00:00:00Z