Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1. - Wikidata - awgldk - TriplyDB

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

http://www.wikidata.org/entity/Q40817514

about

CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression Regulation of NF-κB activation through a novel PI-3K-independent and PKA/Akt-dependent pathway in human umbilical vein endothelial cells An antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues P2Y12 receptor stimulation inhibits beta-adrenergic receptor-induced differentiation by reversing the cyclic AMP-dependent inhibition of protein kinase B Activation of Akt as a mechanism for tumor immune evasion.Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila.Reduced cAMP, Akt activation and p65-c-Rel dimerization: mechanisms involved in the protective effects of mGluR3 agonists in cultured astrocytes.Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells Hepatocyte proliferation during liver regeneration is impaired in mice with methionine diet-induced hyperhomocysteinemia.The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1.Possibility of autocrine beta-adrenergic signaling in C2C12 myotubes {Beta}2-adrenergic receptor agonists inhibit the proliferation of 1321N1 astrocytoma cells.Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.Invited Review: Autocrine/paracrine IGF-I and skeletal muscle adaptation.Inhibition of endothelial cell survival and angiogenesis by protein kinase A TRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling.Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cells Broad-scale phosphoprotein profiling of beta adrenergic receptor (β-AR) signaling reveals novel phosphorylation and dephosphorylation events Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation.JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.Comparative effects of diet and carcinogen on microRNA expression in the stem cell niche of the mouse colonic crypt Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.Chloroquine increases phosphorylation of AMPK and Akt in myotubes.Protein kinase A (PKA) isoform RIIbeta mediates the synergistic killing effect of cAMP and glucocorticoid in acute lymphoblastic leukemia cells Chlorin e6 Prevents ADP-Induced Platelet Aggregation by Decreasing PI3K-Akt Phosphorylation and Promoting cAMP Production.Hindbrain GLP-1 receptor-mediated suppression of food intake requires a PI3K-dependent decrease in phosphorylation of membrane-bound Akt.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Extracellular adenosine regulates naive T cell development and peripheral maintenance.cAMP signaling increases histone deacetylase 8 expression via the Epac2-Rap1A-Akt pathway in H1299 lung cancer cells.5-HT1A receptor-regulated signal transduction pathways in brain.Direct control of caveolin-1 expression by FOXO transcription factors.cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.Expression and functional characterization of P2Y1 and P2Y12 nucleotide receptors in long-term serum-deprived glioma C6 cells.Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites.Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells.

P2860

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P2860

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

http://www.wikidata.org/entity/Q40817514

description

2001 nî lūn-bûn

@nan

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

2001年论文

@zh

2001年论文

@zh-cn

name

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

@en

type

label

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

@en

prefLabel

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

@en

P1433

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P2860

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P698

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P1433

Journal of Biological Chemistry

P1476

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1

@en

P2093

Chung J

http://www.w3.org/2001/XMLSchema#string

Jee K

http://www.w3.org/2001/XMLSchema#string

Kim D

http://www.w3.org/2001/XMLSchema#string

Kim S

http://www.w3.org/2001/XMLSchema#string

P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt

P304

12864-12870

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P31

scholarly article

P356

10.1074/JBC.M001492200

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P407

P433

16

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P478

276

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P577

2001-01-26T00:00:00Z

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12055730

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P698

11278269

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