Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
about
CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppressionRegulation of NF-κB activation through a novel PI-3K-independent and PKA/Akt-dependent pathway in human umbilical vein endothelial cellsAn antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5pGlycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residuesP2Y12 receptor stimulation inhibits beta-adrenergic receptor-induced differentiation by reversing the cyclic AMP-dependent inhibition of protein kinase BActivation of Akt as a mechanism for tumor immune evasion.Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila.Reduced cAMP, Akt activation and p65-c-Rel dimerization: mechanisms involved in the protective effects of mGluR3 agonists in cultured astrocytes.Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cellsHepatocyte proliferation during liver regeneration is impaired in mice with methionine diet-induced hyperhomocysteinemia.The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1.Possibility of autocrine beta-adrenergic signaling in C2C12 myotubes{Beta}2-adrenergic receptor agonists inhibit the proliferation of 1321N1 astrocytoma cells.Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.Invited Review: Autocrine/paracrine IGF-I and skeletal muscle adaptation.Inhibition of endothelial cell survival and angiogenesis by protein kinase ATRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling.Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cellsBroad-scale phosphoprotein profiling of beta adrenergic receptor (β-AR) signaling reveals novel phosphorylation and dephosphorylation eventsMultiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation.JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.Comparative effects of diet and carcinogen on microRNA expression in the stem cell niche of the mouse colonic cryptActivation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.Chloroquine increases phosphorylation of AMPK and Akt in myotubes.Protein kinase A (PKA) isoform RIIbeta mediates the synergistic killing effect of cAMP and glucocorticoid in acute lymphoblastic leukemia cellsChlorin e6 Prevents ADP-Induced Platelet Aggregation by Decreasing PI3K-Akt Phosphorylation and Promoting cAMP Production.Hindbrain GLP-1 receptor-mediated suppression of food intake requires a PI3K-dependent decrease in phosphorylation of membrane-bound Akt.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Extracellular adenosine regulates naive T cell development and peripheral maintenance.cAMP signaling increases histone deacetylase 8 expression via the Epac2-Rap1A-Akt pathway in H1299 lung cancer cells.5-HT1A receptor-regulated signal transduction pathways in brain.Direct control of caveolin-1 expression by FOXO transcription factors.cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulationRegulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.Expression and functional characterization of P2Y1 and P2Y12 nucleotide receptors in long-term serum-deprived glioma C6 cells.Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites.Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells.
P2860
Q26801436-EB730363-6493-4E7D-A064-94AB79AAFA84Q28484247-7B92F4BC-58CB-4188-B123-6F8DBC01A326Q28566847-1E5791A3-B80E-42B0-A39C-107B494E56E6Q28577005-F37D2393-A93C-467A-BCEB-85B1AEE4F0C9Q28581562-8E7505AF-3775-42D8-89BF-7BD73BE9D4B5Q33713327-F5A7033F-F44A-4428-9F3F-3F8C408E5340Q33900458-007EEFC9-EAF0-4979-96B2-166FF7970990Q33968317-4C330E15-B3FD-469B-AF3B-194997F6FD4EQ34093520-7B68B986-779E-45C5-A8C4-004BF776E3EFQ34254452-93B1CC9C-10B6-4F30-82DB-D99E6A3C3DECQ34328370-00267540-AA8B-4CE8-BD88-24918FD09132Q34462191-7B01AE2F-D426-4F8C-B659-50C3B2F83C73Q34552107-F08F0E2E-D67A-42C3-8FC0-01FDE2F046B4Q34784159-0710C0A9-2155-4C67-8D5D-1984C33D0D7EQ34787113-EBC3FDC5-8363-439F-B0D6-F36EBEC2488AQ34797701-47E3BD68-17DF-47A4-A67A-B786BE0DC97DQ34913885-8F7AF548-0A64-4B84-BA9D-6570396C8023Q35046114-69D72F97-E7C2-4714-9ABB-B291292667D1Q35067711-255660A2-77FC-430D-B634-0E11E2D0984AQ35100664-0B0EB3DD-55F2-47B6-A1BB-477EF646CE77Q35222208-65084313-79BA-4FD3-8300-270A284B85C0Q35635353-81F340AB-04DC-4680-8E06-5434D45E3259Q36359569-6872AF0C-883A-4A52-8CEF-C6320DA47CE2Q36478911-C17FE8F4-81F9-495B-A532-8AD1A5E4342BQ36754793-ABDCEF08-02C5-4602-B4A9-8B092BE4838EQ36808503-6ACF4900-C55B-4FF0-B840-02CE076BC66CQ37127241-9EA8CDC4-B2F2-4FDB-AF12-14B440F94825Q37142459-1E5A8954-366C-4220-8DA7-9941368B5065Q37180159-4EFC89C6-3AD5-4190-8551-6DA350E2BE56Q37322177-43B31726-D0D1-4CA0-A194-C08B808E83E9Q37680065-DF9CA274-91B3-4749-A900-476B67372DD8Q37723815-3ED2440D-6EDE-48FC-9B47-FD6B0DE43AF6Q38335920-C396C087-E565-4ABD-BFC2-9A601169CDDCQ38657890-57B907AD-5C92-478A-A298-4DA3C4784BB2Q39972783-C1A96E09-C11F-46DF-9318-E58564655DD8Q40048813-FC7CE753-B3AB-4F38-90A3-223AC3AB47C0Q40159944-78946A79-5625-46F3-998A-C2FBE0AF17E7Q40623088-F4850155-F9F2-41AC-9D37-2BE4F23B6675Q40696307-C6E157BB-82C8-4487-94C1-8D0C59A9FAE2Q40744196-5D1CCFCB-F803-44FD-A3F5-B82679644782
P2860
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
@en
type
label
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
@en
prefLabel
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
@en
P2093
P2860
P356
P1476
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1
@en
P2093
P2860
P304
12864-12870
P356
10.1074/JBC.M001492200
P407
P577
2001-01-26T00:00:00Z