Interferon-gamma down-regulates gene expression of cathepsin K in osteoclasts and inhibits osteoclast formation.
about
Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritisOsteoimmunology and the influence of pro-inflammatory cytokines on osteoclastsAcid phosphatases.Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription.Elevated suppressor of cytokine signaling-1 (SOCS-1): a mechanism for dysregulated osteoclastogenesis in HIV transgenic ratsThe silencing of cathepsin K used in gene therapy for periodontal disease reveals the role of cathepsin K in chronic infection and inflammation.Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation.Molecular mechanisms of the biphasic effects of interferon-γ on osteoclastogenesis.Osteoclasts: New InsightsThe relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues.Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol.In vivo impact of a 4 bp deletion mutation in the DLX3 gene on bone development.Osteoporotic bone of miR-150-deficient mice: Possibly due to low serum OPG-mediated osteoclast activation.Osteoimmunology in orthodontic tooth movement.IL-1alpha stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kappaB pathway.Osteoclast proton pump regulator Atp6v1c1 enhances breast cancer growth by activating the mTORC1 pathway and bone metastasis by increasing V-ATPase activity.Activation status of γδ T cells dictates their effect on osteoclast generation and bone resorption.T-lymphocyte phenotype and function triggered by Aggregatibacter actinomycetemcomitans is serotype-dependent.Crosstalk among IL-23 and DNAX activating protein of 12 kDa-dependent pathways promotes osteoclastogenesisReciprocal effects of Interferon-γ and IL-4 on differentiation to osteoclast-like cells by RANKL or LPS.Immunology of Gut-Bone Signaling.Clcn7F318L/+ as a new mouse model of Albers-Schönberg disease.
P2860
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P2860
Interferon-gamma down-regulates gene expression of cathepsin K in osteoclasts and inhibits osteoclast formation.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Interferon-gamma down-regulate ...... inhibits osteoclast formation.
@en
type
label
Interferon-gamma down-regulate ...... inhibits osteoclast formation.
@en
prefLabel
Interferon-gamma down-regulate ...... inhibits osteoclast formation.
@en
P2093
P2860
P1476
Interferon-gamma down-regulate ...... inhibits osteoclast formation.
@en
P2093
P2860
P304
P356
10.1177/00220345010800011001
P407
P577
2001-01-01T00:00:00Z