Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding.
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Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerasesStructure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexesAssociation of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adultsSteroid Receptor-Associated Immunophilins: A Gateway to Steroid SignallingPolymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatmentThe aryl hydrocarbon receptor complex and the control of gene expressionFKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathwayC-terminal sequences of hsp70 and hsp90 as non-specific anchors for tetratricopeptide repeat (TPR) proteinsExpression and regulation of the Fkbp5 gene in the adult mouse brainFKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroidsRisk and resilience: genetic and environmental influences on development of the stress response.Dexamethasone Treatment Leads to Enhanced Fear Extinction and Dynamic Fkbp5 Regulation in AmygdalaNoncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling.The human glucocorticoid receptor: molecular basis of biologic functionThe helix 1-3 loop in the glucocorticoid receptor LBD is a regulatory element for FKBP cochaperones.Towards the clinical implementation of pharmacogenetics in bipolar disorder.Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids.Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51.The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder.Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptorsPharmacogenomics of suicidal events.Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activityEscherichia coli- and Staphylococcus aureus-induced mastitis differentially modulate transcriptional responses in neighbouring uninfected bovine mammary gland quarters.FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.Control of glucocorticoid and progesterone receptor subcellular localization by the ligand-binding domain is mediated by distinct interactions with tetratricopeptide repeat proteins.Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma.Versatile TPR domains accommodate different modes of target protein recognition and functionFKBP51-a selective modulator of glucocorticoid and androgen sensitivity.FKBP5 genotype-dependent DNA methylation and mRNA regulation after psychosocial stress in remitted depression and healthy controlsEnvironmental stressors and epigenetic control of the hypothalamic-pituitary-adrenal axis.Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ).Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor ProteinsGlucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5.Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes.
P2860
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P2860
Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Squirrel monkey immunophilin F ...... ucocorticoid receptor binding.
@en
type
label
Squirrel monkey immunophilin F ...... ucocorticoid receptor binding.
@en
prefLabel
Squirrel monkey immunophilin F ...... ucocorticoid receptor binding.
@en
P2093
P356
P1433
P1476
Squirrel monkey immunophilin F ...... ucocorticoid receptor binding.
@en
P2093
D L Valentine
J G Scammell
P D Reynolds
P304
P356
10.1210/ENDO.141.11.7785
P407
P577
2000-11-01T00:00:00Z