The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions.
about
High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activationCrystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k): A MYELOID INHIBITORY RECEPTOR INVOLVED IN IMMUNE TOLERANCECrystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA bindingLymphocyte cell-cycle inhibition by HLA-G is mediated by phosphatase SHP-2 and acts on the mTOR pathwayThe co-expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium.HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells.Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages.HLA-G as a tolerogenic molecule in transplantation and pregnancy.Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllersInhibitory NK-cell receptors on T cells: witness of the past, actors of the future.The LILR family: modulators of innate and adaptive immune pathways in health and disease.Differential expression of leukocyte immunoglobulin-like receptors on cord-blood-derived human mast cell progenitors and mature mast cells.S100A9 protein is a novel ligand for the CD85j receptor and its interaction is implicated in the control of HIV-1 replication by NK cells.Association of the LILRA3 deletion with B-NHL and functional characterization of the immunostimulatory molecule.HLA-G and NK receptor are expressed in psoriatic skin: a possible pathway for regulating infiltrating T cells?Amniotic fluid soluble human leukocyte antigen-G in term and preterm parturition, and intra-amniotic infection/inflammationSignaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment.A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cellsTLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.Functions of HLA-G in the immune system.Structural immunology and crystallography help immunologists see the immune system in action: how T and NK cells touch their ligands.Natural killer cells and malignant haemopathies: a model for the interaction of cancer with innate immunity.The emerging role of leukocyte immunoglobulin-like receptors (LILRs) in HIV-1 infection.Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors.Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging.Latent Cytomegalovirus Infection in Rheumatoid Arthritis and Increased Frequencies of Cytolytic LIR-1+CD8+ T Cells.Cis association of leukocyte Ig-like receptor 1 with MHC class I modulates accessibility to antibodies and HCMV UL18.Impact of the NK cell receptor LIR-1 (ILT-2/CD85j/LILRB1) on cytotoxicity against multiple myeloma.LILRB receptor-mediated regulation of myeloid cell maturation and function.CD85/LIR-1/ILT2 and CD152 (cytotoxic T lymphocyte antigen 4) inhibitory molecules down-regulate the cytolytic activity of human CD4+ T-cell clones specific for Mycobacterium tuberculosisInhibitory receptors CD85j, LAIR-1, and CD152 down-regulate immunoglobulin and cytokine production by human B lymphocytes.Switch of HLA-G alternative splicing in a melanoma cell line causes loss of HLA-G1 expression and sensitivity to NK lysis.Genetic variability of the major histocompatibility complex class I homologue encoded by human cytomegalovirus leads to differential binding to the inhibitory receptor ILT2.Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors.Modulation of the inhibitory receptor leukocyte Ig-like receptor 1 on human natural killer cells.Altered pattern of major histocompatibility complex expression in renal carcinoma: tumor-specific expression of the nonclassical human leukocyte antigen-G molecule is restricted to clear cell carcinoma while up-regulation of other major histocompatiFinding Balance: T cell Regulatory Receptor Expression during Aging.Activation-induced upregulation of inhibitory killer Ig-like receptors is regulated by protein kinase C.LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions.Ig-like transcript 2 (ILT2) suppresses T cell function in chronic lymphocytic leukemia.
P2860
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P2860
The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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2000年學術文章
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name
The CD85/LIR-1/ILT2 inhibitory ...... own-regulates their functions.
@en
type
label
The CD85/LIR-1/ILT2 inhibitory ...... own-regulates their functions.
@en
prefLabel
The CD85/LIR-1/ILT2 inhibitory ...... own-regulates their functions.
@en
P2093
P1476
The CD85/LIR-1/ILT2 inhibitory ...... own-regulates their functions.
@en
P2093
Anastasi G
Saverino D
P304
P356
10.4049/JIMMUNOL.165.7.3742
P407
P577
2000-10-01T00:00:00Z