Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity.
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Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration.How do kinases contribute to tonicity-dependent regulation of the transcription factor NFAT5?Hypotonic activation of the myo-inositol transporter SLC5A3 in HEK293 cells probed by cell volumetry, confocal and super-resolution microscopyMouse TonEBP-NFAT5: expression in early development and alternative splicingTonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5)Hyperosmotic stress signaling to the nucleus disrupts the Ran gradient and the production of RanGTPDetermination of the NFAT5/TonEBP transcription factor in the human and ovine placentaOsmotic stress regulates mineralocorticoid receptor expression in a novel aldosterone-sensitive cortical collecting duct cell line.NFAT5 is activated by hypoxia: role in ischemia and reperfusion in the rat kidney.cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding protein.Hippocampal betaine/GABA transporter mRNA expression is not regulated by inflammation or dehydration post-status epilepticus.Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBPDownregulation of the taurine transporter TauT during hypo-osmotic stress in NIH3T3 mouse fibroblastsPlacental TonEBP/NFAT5 osmolyte regulation in an ovine model of intrauterine growth restrictionNFAT5 contributes to osmolality-induced MCP-1 expression in mesothelial cellsExpression, fermentation and purification of a predicted intrinsically disordered region of the transcription factor, NFAT5Mutations that reduce its specific DNA binding inhibit high NaCl-induced nuclear localization of the osmoprotective transcription factor NFAT5Novel nuclear localization signal regulated by ambient tonicity in vertebratesNFAT5 in cellular adaptation to hypertonic stress - regulations and functional significanceNF-kappaB modulates aquaporin-2 transcription in renal collecting duct principal cells.NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment.Urea and NaCl regulate UT-A1 urea transporter in opposing directions via TonEBP pathway during osmotic diuresis.ZAC1 is up-regulated by hypertonicity and decreases sorbitol dehydrogenase expression, allowing accumulation of sorbitol in kidney cells.Hypertonic stress in the kidney: a necessary evil.NFAT5 genes are part of the osmotic regulatory system in Atlantic salmon (Salmo salar).14-3-3-β and -{varepsilon} contribute to activation of the osmoprotective transcription factor NFAT5 by increasing its protein abundance and its transactivating activity.The betaine/GABA transporter and betaine: roles in brain, kidney, and liver.Osmolality/salinity-responsive enhancers (OSREs) control induction of osmoprotective genes in euryhaline fish.NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.Phosphorylation by casein kinase 1 regulates tonicity-induced osmotic response element-binding protein/tonicity enhancer-binding protein nucleocytoplasmic trafficking.TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity.The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP.TonEBP is inhibited by RNA helicase A via interaction involving the E'F loop.Regulation of TonEBP transcriptional activator in MDCK cells following changes in ambient tonicity.Rottlerin inhibits tonicity-dependent expression and action of TonEBP in a PKCdelta-independent fashion.Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity.Role of NFAT5 in inflammatory disorders associated with osmotic stress.Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents.Subcellular redistribution of the renal betaine transporter during hypertonic stress.Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro.
P2860
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P2860
Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity.
description
2000 nî lūn-bûn
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name
Bidirectional regulation of to ...... sponse to changes in tonicity.
@en
type
label
Bidirectional regulation of to ...... sponse to changes in tonicity.
@en
prefLabel
Bidirectional regulation of to ...... sponse to changes in tonicity.
@en
P2093
P1476
Bidirectional regulation of to ...... sponse to changes in tonicity.
@en
P2093
P304
P356
10.1152/AJPRENAL.2000.278.6.F1006
P577
2000-06-01T00:00:00Z