Depletion of p18/LAMTOR1 promotes cell survival via activation of p27(kip1) -dependent autophagy under starvation.

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UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity

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Q56534093-A0C8FAA8-2574-4469-858A-959840D5CAB0

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Depletion of p18/LAMTOR1 promotes cell survival via activation of p27(kip1) -dependent autophagy under starvation.

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Depletion of p18/LAMTOR1 promo ...... nt autophagy under starvation.

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Depletion of p18/LAMTOR1 promo ...... nt autophagy under starvation.

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Depletion of p18/LAMTOR1 promo ...... nt autophagy under starvation.

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Depletion of p18/LAMTOR1 promo ...... nt autophagy under starvation.

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Deok Ryong Kim

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Hae Sook Noh

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Ji Hye Ha

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Jong Ryeal Hahm

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Sahib Zada

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Seon Mi Baek

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P2860

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis

Mammalian autophagy: core molecular machinery and signaling regulation

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.

Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

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1242-1250

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scholarly article

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10.1002/CBIN.10497

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2015-06-01T00:00:00Z

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26032166

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P921

autophagy

Depletion of p18/LAMTOR1 promotes cell survival via activation of p27(kip1) -dependent autophagy under starvation.

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P2860

P2860

Depletion of p18/LAMTOR1 promotes cell survival via activation of p27(kip1) -dependent autophagy under starvation.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921