The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
about
MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration.Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acidsMetabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1Raf family kinases: old dogs have learned new tricksPdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasisRegulation of TOR by small GTPasesSpatial regulation of the mTORC1 system in amino acids sensing pathwayThe Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationConserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingEndosome maturationRegulation of mTORC1 by amino acidsVacuoles in mammals: a subcellular structure indispensable for early embryogenesisRoles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysisVEGF signaling inside vascular endothelial cells and beyond.Location, location, location: is membrane partitioning everything when it comes to innate immune activation?TFEB at a glanceBeyond indigestion: emerging roles for lysosome-based signaling in human diseaseRegulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networksSpatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosomeSimulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilinArf4 is required for Mammalian development but dispensable for ciliary assemblyEstrogen receptor alpha is expressed in mesenteric mesothelial cells and is internalized in caveolae upon Freund's adjuvant treatmentEndocytosis and signalling: intertwining molecular networksThe transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis.Ras transformation uncouples the kinesin-coordinated cellular nutrient responseNutrient signaling to mTOR and cell growth.LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signallingTracing the Archaeal Origins of Eukaryotic Membrane-Trafficking System Building Blocks.Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer riskIdentification of host proteins interacting with the integrin-like A domain of Toxoplasma gondii micronemal protein MIC2 by yeast-two-hybrid screening.The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cellsLipid raft redox signaling: molecular mechanisms in health and disease.MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in miceLAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cellsRedox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.p18, a novel adaptor protein, regulates pulmonary endothelial barrier function via enhanced endocytic recycling of VE-cadherin.A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells.
P2860
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P248
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P2860
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The novel lipid raft adaptor p ...... -ERK pathway to late endosomes
@nl
The novel lipid raft adaptor p ...... ERK pathway to late endosomes.
@ast
The novel lipid raft adaptor p ...... ERK pathway to late endosomes.
@en
type
label
The novel lipid raft adaptor p ...... -ERK pathway to late endosomes
@nl
The novel lipid raft adaptor p ...... ERK pathway to late endosomes.
@ast
The novel lipid raft adaptor p ...... ERK pathway to late endosomes.
@en
prefLabel
The novel lipid raft adaptor p ...... -ERK pathway to late endosomes
@nl
The novel lipid raft adaptor p ...... ERK pathway to late endosomes.
@ast
The novel lipid raft adaptor p ...... ERK pathway to late endosomes.
@en
P2093
P2860
P921
P3181
P356
P1433
P1476
The novel lipid raft adaptor p ...... -ERK pathway to late endosomes
@en
P2093
Akihiro Hondo
Atsuko Kasai
Kazunobu Saito
Masato Okada
Shigeyki Nada
Yasuo Uchiyama
P2860
P304
P3181
P356
10.1038/EMBOJ.2008.308
P407
P50
P577
2009-01-29T00:00:00Z