Protein kinase C phosphorylates and regulates UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.
about
The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesisHereditary inclusion body myopathy: a decade of progressAberrant O-GlcNAcylation disrupts GNE enzyme activity in GNE myopathy.Sialylation is essential for early development in mice.UDP-GlcNAc 2-Epimerase/ManNAc Kinase (GNE): A Master Regulator of Sialic Acid Synthesis.Identification, tissue distribution, and molecular modeling of novel human isoforms of the key enzyme in sialic acid synthesis, UDP-GlcNAc 2-epimerase/ManNAc kinase.Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.Metabolic Glycoengineering with N-Acyl Side Chain Modified Mannosamines.The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy.Lec3 Chinese hamster ovary mutants lack UDP-N-acetylglucosamine 2-epimerase activity because of mutations in the epimerase domain of the Gne gene.Function and Mutations of the GNE Gene Leading to Distal Myopathy with Rimmed Vacuoles/Hereditary Inclusion-Body Myopathy, Animal Models, and Potential Treatment
P2860
Q24318382-44D9E794-9539-456E-9429-9CD34A58DD49Q28251720-41DED196-F3E2-4333-89D9-E14918090025Q30315345-456720AA-4AEC-42C3-AE80-9CFEEE9756C4Q34024283-1423B34C-BA0D-470A-8695-DB286ADF8F4BQ34167791-0A25051C-2255-4CEA-9947-F015D4F6B5ACQ35336353-4A6CF4AA-DCFA-4DA8-A07E-512D50ACE1D1Q37474841-692B16F7-AF72-4DB9-A4B7-C4937E7AB20EQ38902441-A552D9A3-C586-49E3-903E-2AE520E86285Q40555085-8AD1E6D7-80A9-467F-9BAC-094E8A3CE46BQ40625765-6D1C5036-6D9E-430D-8A0B-EAF14B2E176BQ58036228-98E5F38D-B6F0-4E7F-987C-A7F2B33B5771
P2860
Protein kinase C phosphorylates and regulates UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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2000年學術文章
@zh-hant
name
Protein kinase C phosphorylate ...... se/N-acetylmannosamine kinase.
@en
type
label
Protein kinase C phosphorylate ...... se/N-acetylmannosamine kinase.
@en
prefLabel
Protein kinase C phosphorylate ...... se/N-acetylmannosamine kinase.
@en
P2093
P2860
P1433
P1476
Protein kinase C phosphorylate ...... se/N-acetylmannosamine kinase.
@en
P2093
P2860
P304
P356
10.1016/S0014-5793(00)01331-4
P407
P577
2000-03-01T00:00:00Z