Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin.
about
VEGF-initiated angiogenesis and the uPA/uPAR systemIdentification of the disulfide bonds in the recombinant somatomedin B domain of human vitronectinSoluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling.uPAR-induced cell adhesion and migration: vitronectin provides the keyRandom peptide bacteriophage display as a probe for urokinase receptor ligands.Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region.Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence.The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis.Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing.Density enhanced phosphatase-1 down-regulates urokinase receptor surface expression in confluent endothelial cellsConformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.Mimicry of the regulatory role of urokinase in lamellipodia formation by introduction of a non-native interdomain disulfide bond in its receptor.A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogenFluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor.Lipid rafts: integrated platforms for vascular organization offering therapeutic opportunities.Sequences within domain II of the urokinase receptor critical for differential ligand recognition.Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin.Dimerization controls the lipid raft partitioning of uPAR/CD87 and regulates its biological functions.Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide.Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor.The cleavage of the urokinase receptor regulates its multiple functions.Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin.Vitronectin in human hepatic tumours contributes to the recruitment of lymphocytes in an alpha v beta3-independent manner.
P2860
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P2860
Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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@zh-my
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name
Domain 1 of the urokinase rece ...... d cell binding to vitronectin.
@en
type
label
Domain 1 of the urokinase rece ...... d cell binding to vitronectin.
@en
prefLabel
Domain 1 of the urokinase rece ...... d cell binding to vitronectin.
@en
P2860
P1433
P1476
Domain 1 of the urokinase rece ...... d cell binding to vitronectin.
@en
P2093
P2860
P356
10.1016/S0014-5793(00)01282-5
P407
P577
2000-03-01T00:00:00Z