Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations.
about
Nonsense-mediated mRNA decay: novel mechanistic insights and biological impactThe dharma of nonsense-mediated mRNA decay in mammalian cellsGene expression regulation by upstream open reading frames and human diseaseNonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryOrganizing principles of mammalian nonsense-mediated mRNA decayEukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanismsHigh-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE.Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels.Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.NMD: At the crossroads between translation termination and ribosome recycling.Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase ActivityRecent transcriptome-wide mapping of UPF1 binding sites reveals evidence for its recruitment to mRNA before translation.Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay.Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.Ataluren as an agent for therapeutic nonsense suppression.NMD: a multifaceted response to premature translational termination.Nonsense-mediated mRNA decay: from mechanistic insights to impacts on human health.Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay.Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity.Dual function of UPF3B in early and late translation termination.Cytoplasmic poly(A) binding protein-1 binds to genomically encoded sequences within mammalian mRNAs.Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle.An RNA decay factor wears a new coat: UPF3B modulates translation termination.New functions in translation termination uncovered for NMD factor UPF3B.eIF3: a factor for human health and disease.New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors.
P2860
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P2860
Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Interaction of PABPC1 with the ...... G-proximal nonsense mutations.
@en
type
label
Interaction of PABPC1 with the ...... G-proximal nonsense mutations.
@en
prefLabel
Interaction of PABPC1 with the ...... G-proximal nonsense mutations.
@en
P2860
P50
P356
P1476
Interaction of PABPC1 with the ...... UG-proximal nonsense mutations
@en
P2093
Cristina Barbosa
Stephen A Liebhaber
P2860
P304
P356
10.1093/NAR/GKR820
P577
2011-10-11T00:00:00Z