Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.

Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.

Item
http://www.wikidata.org/entity/Q40900620
Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells.Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia.Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action.Neuroprotective effect of asiatic acid on rotenone-induced mitochondrial dysfunction and oxidative stress-mediated apoptosis in differentiated SH-SYS5Y cells.Asiatic acid exerts anticancer potential in human ovarian cancer cells via suppression of PI3K/Akt/mTOR signalling.Synthesis, anti-tumor and anti-angiogenic activity evaluations of asiatic Acid amino Acid derivatives.The centella asiatica juice effects on DNA damage, apoptosis and gene expression in hepatocellular carcinoma (HCC).Asiatic acid attenuates pre-neoplastic lesions, oxidative stress, biotransforming enzymes and histopathological alterations in 1,2-dimethylhydrazine-induced experimental rat colon carcinogenesis.Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.Asiatic acid derivatives enhance cognitive performance partly by improving acetylcholine synthesis.Effect of asiatic acid on the Ang II-AT1R-NADPH oxidase-NF-κB pathway in renovascular hypertensive rats.Efficacy of Natural Compounds in Neurodegenerative Disorders.An Investigation of the Differential Effects of Ursane Triterpenoids from Centella asiatica, and Their Semisynthetic Analogues, on GABAA Receptors.Antiangiogenic effects of AA-PMe on HUVECs in vitro and zebrafish in vivo.Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise
P2860

Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.

Item
http://www.wikidata.org/entity/Q40900620
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Structure-activity relationshi ...... A beta)-induced neurotoxicity.
@en
type
label
Structure-activity relationshi ...... A beta)-induced neurotoxicity.
@en
prefLabel
Structure-activity relationshi ...... A beta)-induced neurotoxicity.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Structure-activity relationshi ...... A beta)-induced neurotoxicity.
@en
P2093
P304
P31
P356
10.1016/S0960-894X(99)00658-7
P407
P433
P478
P577
P698
P921