An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression.
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Ancient and recent positive selection transformed opioid cis-regulation in humansκ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addictionA genetic polymorphism of the endogenous opioid dynorphin modulates monetary reward anticipation in the corticostriatal loopRegulation of mu-opioid receptor gene transcription by interleukin-4 and influence of an allelic variation within a STAT6 transcription factor binding siteFrequent gain and loss of functional transcription factor binding sites.Neurobiology of dysregulated motivational systems in drug addiction.Abundant raw material for cis-regulatory evolution in humans.Implications of genome wide association studies for addiction: are our a priori assumptions all wrong?Dynamic up-regulation of prodynorphin transcription in temporal lobe epilepsyPharmacotherapy of addictions.When the DREAM is gone: from basic science to future prospectives in pain management and beyond.Differentiation and fiber type-specific activity of a muscle creatine kinase intronic enhancerAlcohol dependence, disinhibited behavior and variation in the prodynorphin geneA functional polymorphism in the prodynorphin gene affects cognitive flexibility and brain activation during reversal learning.Genetics of temporal lobe epilepsy: a review.Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression.Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors.Polymorphisms of the kappa opioid receptor and prodynorphin genes: HIV risk and HIV natural history.Dynorphin and the pathophysiology of drug addiction.The genetics of the opioid system and specific drug addictionsRole of a functional human gene polymorphism in stress responsivity and addictionsSearch for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.Bidirectional translational research: Progress in understanding addictive diseasesA functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain.The dynorphin/κ-opioid receptor system and its role in psychiatric disorders.Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity.A Functional 3'UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits.Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs.Association between VNTR Polymorphism in Promoter Region of Prodynorphin (PDYN) Gene and Methamphetamine Dependence.Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse.Early modulation by the dopamine D4 receptor of morphine-induced changes in the opioid peptide systems in the rat caudate putamen.Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain.Prodynorphin gene promoter repeat associated with cocaine/alcohol codependence.Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.Sequence upstream of the wheat (Triticum aestivum L.) ALMT1 gene and its relationship to aluminum resistance.Prodynorphin gene promoter polymorphism and temporal lobe epilepsy: A meta-analysis.Gender-specific association of functional prodynorphin 68 bp repeats with cannabis exposure in an African American cohort.Evaluation of prodynorphin gene polymorphisms and their association with heroin addiction in a sample of the southeast Iranian population.A functional polymorphism in the prodynorphin gene promotor is associated with temporal lobe epilepsy
P2860
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P2860
An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
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2000年學術文章
@zh-hant
name
An allelic variation in the hu ...... s stimulus-induced expression.
@en
type
label
An allelic variation in the hu ...... s stimulus-induced expression.
@en
prefLabel
An allelic variation in the hu ...... s stimulus-induced expression.
@en
P2093
P1476
An allelic variation in the hu ...... s stimulus-induced expression.
@en
P2093
P304
P356
10.1046/J.1471-4159.2000.740472.X
P407
P577
2000-02-01T00:00:00Z