Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?
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Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like MechanismIn vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.Vitamin A and Alzheimer's diseaseDeficiency of disulfide bonds facilitating fibrillogenesis of endostatinNeurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratioLeu138 in bovine prion peptide fibrils is involved in seeding discrimination related to codon 129 M/V polymorphism in the prion peptide seeding experimentTransmission of prionsStructure of the cross-beta spine of amyloid-like fibrilsPropagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factorConversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteinsDarwinian evolution of prions in cell cultureMolecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseasesAmyloids: friend or foe?Aggregation and disaggregation of senile plaques in Alzheimer diseaseMedin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloidPhosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosisLoss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer diseaseThe Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR studyPrions, prion-like prionoids, and neurodegenerative disordersThe amyloid hypothesis of Alzheimer's disease at 25 yearsThe role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseasesFluorescent proteins as genetically encoded FRET biosensors in life sciencesγ-Secretase inhibitors and modulators.Fibrillogenesis of huntingtin and other glutamine containing proteinsBehavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Disrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal modelsSelf-propagation of pathogenic protein aggregates in neurodegenerative diseasesA flash in the pan: dissecting dynamic amyloid intermediates using fluorescenceCross-seeding of misfolded proteins: implications for etiology and pathogenesis of protein misfolding diseasesInvestigating the spreading and toxicity of prion-like proteins using the metazoan model organism C. elegansTreatment of Prion Disease with Heterologous Prion ProteinsSpreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegansA helical structural nucleus is the primary elongating unit of insulin amyloid fibrilsA condensation-ordering mechanism in nanoparticle-catalyzed peptide aggregation.Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: A structural clue to amyloid assemblyMolecular mechanisms for protein-encoded inheritanceCrystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion DiseaseAtomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic 2-microglobulin variantAtomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion DiseaseCrystal Structure of a Human Prion Protein Fragment Reveals a Motif for Oligomer Formation
P2860
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P2860
Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Seeding "one-dimensional cryst ...... zheimer's disease and scrapie?
@en
type
label
Seeding "one-dimensional cryst ...... zheimer's disease and scrapie?
@en
prefLabel
Seeding "one-dimensional cryst ...... zheimer's disease and scrapie?
@en
P1433
P1476
Seeding "one-dimensional cryst ...... zheimer's disease and scrapie?
@en
P2093
Jarrett JT
Lansbury PT Jr
P304
P356
10.1016/0092-8674(93)90635-4
P407
P577
1993-06-01T00:00:00Z