The alpha-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs.
about
Oxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytesAmino-acid-dependent signal transduction.Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and SensitivityInactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.Class II phosphoinositide 3-kinase C2alpha: what we learned so farRACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.Insulin inhibition of protein degradation in cells expressing wild-type and mutant insulin receptors.Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases.
P2860
Q28363257-E82A9E03-7A4C-4A3D-B7AC-FFB11074D223Q34066345-BE5E0F1F-2C0E-4A63-ADCE-6FF1AF9953B3Q36363079-8A33F961-96BC-4455-8BAB-5BAC664B56A0Q36990083-FFAD6F1A-2EA5-4C05-B20B-14B28D0368EDQ37589982-D477C07E-84A0-419D-A6D7-335312E1B66EQ38409013-63D1CC8D-6AC6-4C1E-B814-76FD72F6B710Q38561747-C620BC7F-A553-477D-9322-EC74CAB626CDQ43966292-27603612-862A-483B-8949-DED5270F6661Q44791386-EFC8CC0D-7F0C-4A3D-8321-8ACD544879FCQ45202860-A860B6A9-5AF4-4E78-A1A1-D8C96B17F4C4
P2860
The alpha-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
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1999年學術文章
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name
The alpha-isoform of class II ...... requires receptor NPEY motifs.
@en
type
label
The alpha-isoform of class II ...... requires receptor NPEY motifs.
@en
prefLabel
The alpha-isoform of class II ...... requires receptor NPEY motifs.
@en
P2093
P2860
P1433
P1476
The alpha-isoform of class II ...... requires receptor NPEY motifs.
@en
P2093
P2860
P304
P356
10.1016/S0014-5793(99)01388-5
P407
P577
1999-11-01T00:00:00Z