12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.
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A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locusThree human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pterExpression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophagesActivation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular productsComplete degradation of type X collagen requires the combined action of interstitial collagenase and osteoclast-derived cathepsin-B.Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma.Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4.Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.Urokinase receptor is a multifunctional protein: influence of receptor occupancy on macrophage gene expressionAngiopoietin-1-expressing adipose stem cells genetically modified with baculovirus nanocomplex: investigation in rat heart with acute infarction.Collagenase and fibronectin in bronchoalveolar lavage fluid in patients with sarcoidosisA family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kappa B subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells.Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblastsTissue-specific expression and developmental regulation of the human fgr proto-oncogene.Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model.The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli.S6 kinase 2 is bound to chromatin-nuclear matrix cellular fractions and is able to phosphorylate histone H3 at threonine 45 in vitro and in vivo.Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.Effect of Mycobacterium tuberculosis and its components on macrophages and the release of matrix metalloproteinasesSynthesis and secretion of high- and low-molecular-weight forms of the enzyme-releasing peptide (ERP) from the macrophage-like cell line THP-1.Phthaloyl-glycylP-isoleucyl-tryptophan benzylamide is a potent inhibitor of human skin fibroblast collagenase with a Ki of 25 nM.Release of gelatinase and superoxide from human mononuclear phagocytes in response to particulate Tamm Horsfall protein.Lipopolysaccharide modulates the expression of alpha 1 proteinase inhibitor and other serine proteinase inhibitors in human monocytes and macrophages.Elastin degradation by human alveolar macrophages. A prominent role of metalloproteinase activity.
P2860
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P2860
12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
12-o-Tetradecanoyl-phorbol-13- ...... ular elastase and cathepsin G.
@en
type
label
12-o-Tetradecanoyl-phorbol-13- ...... ular elastase and cathepsin G.
@en
prefLabel
12-o-Tetradecanoyl-phorbol-13- ...... ular elastase and cathepsin G.
@en
P2093
P2860
P356
P1476
12-o-Tetradecanoyl-phorbol-13- ...... ular elastase and cathepsin G.
@en
P2093
H G Welgus
N L Connolly
R M Senior
P2860
P304
P356
10.1172/JCI112485
P407
P577
1986-05-01T00:00:00Z