Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro.
about
Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cellsIn prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damagePoly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recoveryKu protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cellsPoly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53Therapeutic Implications for Overcoming Radiation Resistance in Cancer TherapyTNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1Comprehensive SNP scan of DNA repair and DNA damage response genes reveal multiple susceptibility loci conferring risk to tobacco associated leukoplakia and oral cancerTrp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signalingPARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathwaysStrategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy.DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integrationPostischemic poly (ADP-ribose) polymerase (PARP) inhibition reduces ischemia reperfusion injury in a hind-limb ischemia model.The role of ADP-ribosylation in regulating DNA double-strand break repairInputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stressParp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells.ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A.Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer.PARP regulates nonhomologous end joining through retention of Ku at double-strand breaksCXC chemokine ligand 12 protects pancreatic β-cells from necrosis through Akt kinase-mediated modulation of poly(ADP-ribose) polymerase-1 activity.The life and death of DNA-PK.Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress.Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability.PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis.Role of poly(ADP-ribose) polymerase during vascular reconstruction.Protein kinase C protects from DNA damage-induced necrotic cell death by inhibiting poly(ADP-ribose) polymerase-1The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.Bioorthogonal approach to identify unsuspected drug targets in live cells.Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.Altered RECQL5 expression in urothelial bladder carcinoma increases cellular proliferation and makes RECQL5 helicase activity a novel target for chemotherapy.New links between mRNA polyadenylation and diverse nuclear pathways.DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1.Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair.Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines.PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.PARP-1: Friend or Foe of DNA Damage and Repair in Tumorigenesis?Activation of PARP-1 in response to bleomycin depends on the Ku antigen and protein phosphatase 5.The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1.
P2860
Q21563320-D07A0912-4A52-4BEA-BC11-5846A012CB98Q24305228-7994BD99-5BE0-4EC2-A106-CCCA7F20F817Q24793335-0DE918C2-EAB3-482E-8C93-4DD27AC5DA74Q24812323-50F23A36-6931-43BE-8EA5-E79F462C5CA4Q25256778-9F052727-F140-4553-BD18-06DC6558FA11Q26777016-6FDA7D3C-4ACD-484F-8230-FC02F14CE1DBQ28115068-109E2E8B-FA4C-44AC-AEC8-095B9D30AFB9Q28394617-2CD06712-A4FE-46CA-9573-3F5021CCC992Q28910464-4117A7A5-20D2-413B-A49D-1B083A5B4A9CQ29616041-A202104B-A30D-42DD-A69C-F66962AD129FQ33649555-6E51AC1C-AC99-4F67-B00C-D332287602C7Q33835321-5EAFB6D3-1492-4104-A7F8-3E88411BE783Q33915402-ADE7A9E0-6828-4DDC-BA40-BA8D5D7D432FQ34029929-3935EB37-A081-410E-9A84-5FF5FE903D51Q34432293-1791C783-7E9A-469A-8746-DAB9278F5473Q34500845-07DB9A0E-2804-42E1-9FF8-D7FA95EAAD00Q34605890-CB6F2E5E-0C26-4FDC-B592-9B83434211AFQ34982593-5D0CDD40-14D6-4C4B-9F19-BE9232B8E25DQ35156963-FD85672B-AF75-4C43-83CE-4F3A85DBEB15Q35200250-E849CE87-BD59-43A6-BE85-E5EAB4FC6F45Q35980970-1927753F-A746-486B-BD26-CB8024A4FD3CQ36149816-1C67FAE7-7E59-41D5-932A-6A1AE94AF9EBQ36228488-CFFDCC31-3FE4-4815-865F-2C5EB7046BF1Q36377992-6A5B326D-1AFE-4C0B-BA7E-C2E61055967CQ36454901-AA31577E-C4B4-4E78-B540-B359E4FA7D03Q36675624-587B272B-C1B4-4258-A02B-76FCDE801194Q37267855-3BD0F645-A13D-4CED-B005-9F2E1A3B35AEQ37295146-0B2F0CF0-B4D5-4097-B9E3-062435963B59Q37346311-29A737B7-7310-4EF5-ADF2-AF720198B615Q37376761-5048B000-398C-496D-BE3C-6B9C998B7ED2Q37644563-6DAB6EE3-30BD-4A17-9161-9549CA60E621Q37689080-5176EA59-38E2-4D90-A3A6-618BFBCB2EE4Q38235716-4B5F6FB1-1307-44EA-BA9A-4834D79EA703Q39138266-8E0745D8-1506-4EE5-B72A-BD5AE613F773Q39604482-17EA4B22-CBFA-46F9-B35B-3E9795BBB189Q39830817-7B18DC4D-B16D-4CBC-B537-185EC37A130EQ41867379-1FF49A59-B91E-4F2C-B7EC-588DF443260DQ42107975-EC1C2B60-DDE9-493E-8EFE-22529B239681Q42466349-07D3918A-F708-4E7F-89D5-C51296C8A0D1Q43750943-33FD55AF-0999-4CE9-89F4-7B0FD971BB19
P2860
Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Suppression of the poly(ADP-ri ...... ndent protein kinase in vitro.
@en
type
label
Suppression of the poly(ADP-ri ...... ndent protein kinase in vitro.
@en
prefLabel
Suppression of the poly(ADP-ri ...... ndent protein kinase in vitro.
@en
P2093
P356
P1433
P1476
Suppression of the poly(ADP-ri ...... ndent protein kinase in vitro.
@en
P2093
K Shimotohno
M Hatanaka
M Masutani
T D Copeland
T Sugimura
P2888
P304
P356
10.1038/SJ.ONC.1202823
P407
P577
1999-08-01T00:00:00Z
P5875
P6179
1046973765