The CD3-gamma delta epsilon transducing module mediates CD38-induced protein-tyrosine kinase and mitogen-activated protein kinase activation in Jurkat T cells.
about
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathologyPhosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity.Mechanisms of deficient type I protein kinase A activity in lupus T lymphocytes.Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.CD38 autoimmunity: recent advances and relevance to human diabetes.ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary.Antibody mimicry, receptors and clinical applications.CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism.CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.Signaling through CD38 induces NK cell activation.CD38 expression and NAD+-induced intracellular Ca+ mobilization in isolated retinal Müller cells.CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor.CD38 is expressed selectively during the activation of a subset of mature T cells with reduced proliferation but improved potential to produce cytokines.The CD19/CD81 complex physically interacts with CD38 but is not required to induce proliferation in mouse B lymphocytes
P2860
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P2860
The CD3-gamma delta epsilon transducing module mediates CD38-induced protein-tyrosine kinase and mitogen-activated protein kinase activation in Jurkat T cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
The CD3-gamma delta epsilon tr ...... activation in Jurkat T cells.
@en
type
label
The CD3-gamma delta epsilon tr ...... activation in Jurkat T cells.
@en
prefLabel
The CD3-gamma delta epsilon tr ...... activation in Jurkat T cells.
@en
P2860
P50
P356
P1476
The CD3-gamma delta epsilon tr ...... e activation in Jurkat T cells
@en
P2093
P2860
P304
20633-20642
P356
10.1074/JBC.274.29.20633
P407
P577
1999-07-01T00:00:00Z