Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts.
about
Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitorProximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signalingBcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell lineCalcium and apoptosis: facts and hypotheses.Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum.A systematic assessment of mitochondrial function identified novel signatures for drug-induced mitochondrial disruption in cells.Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry.An atypical caspase-independent death pathway for an immunogenic cancer cell line.MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release.Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway.Relationships of diverse apoptotic death process patterns to mitochondrial membrane potential (Δψ(m)) evaluated by three-parameter flow cytometric analysis.Translation initiation factor 4E blocks endoplasmic reticulum-mediated apoptosis.Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event.Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis.Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins.The coxsackievirus 2B protein suppresses apoptotic host cell responses by manipulating intracellular Ca2+ homeostasis.Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis.
P2860
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P2860
Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Bcl-2 targeted to the endoplas ...... toposide in Rat-1 fibroblasts.
@en
type
label
Bcl-2 targeted to the endoplas ...... toposide in Rat-1 fibroblasts.
@en
prefLabel
Bcl-2 targeted to the endoplas ...... toposide in Rat-1 fibroblasts.
@en
P2093
P2860
P50
P356
P1433
P1476
Bcl-2 targeted to the endoplas ...... toposide in Rat-1 fibroblasts.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202716
P407
P577
1999-06-01T00:00:00Z
P5875
P6179
1028837167