CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs.
about
Biology of recently discovered cytokines: interleukin-17--a unique inflammatory cytokine with roles in bone biology and arthritisTTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activationA diverse family of proteins containing tumor necrosis factor receptor-associated factor domainsMolecular basis for CD40 signaling mediated by TRAF3Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expressionCrystallographic analysis of CD40 recognition and signaling by human TRAF2The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption.Crystallographic and Mutational Analysis of the CD40-CD154 Complex and Its Implications for Receptor ActivationTRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosisTumor necrosis factor receptor-associated factors (TRAFs)Molecular characterization of CD40 signaling intermediatesTRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.The rise and fall of long-lived humoral immunity: terminal differentiation of plasma cells in health and disease.The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells.Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors.TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRsContribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus.Tumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans.Regulation of CD40 function by its isoforms generated through alternative splicing.Structural and biochemical analysis of signal transduction by the TRAF family of adapter proteins.Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1Ligation of CD40 receptor in human B lymphocytes triggers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK.Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1).Beta3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice.Nuclear transcription factor-kappaB in Hodgkin's disease.Chaperokine-induced signal transduction pathways.Herpesvirus saimiri STP-A oncoprotein utilizes Src family protein tyrosine kinase and tumor necrosis factor receptor-associated factors to elicit cellular signal transductionThe in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiationHuman immunodeficiency virus type 1-associated CD40 ligand transactivates B lymphocytes and promotes infection of CD4+ T cells.Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signalingThe LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis.The programmed death-1 and interleukin-10 pathways play a down-modulatory role in LP-BM5 retrovirus-induced murine immunodeficiency syndrome.Myeloid-derived suppressor cells in murine retrovirus-induced AIDS inhibit T- and B-cell responses in vitro that are used to define the immunodeficiencyStructure-function relationships in the IL-17 receptor: implications for signal transduction and therapyTRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.Molecular mechanism and function of CD40/CD40L engagement in the immune system.The role of CD40 and CD154/CD40L in dendritic cells.TRAF-mediated regulation of immune and inflammatory responses.Tuning of CD40-CD154 interactions in human B-lymphocyte activation: a broad array of in vitro models for a complex in vivo situation.
P2860
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P2860
CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
CD40 signaling through tumor n ...... am pathways by distinct TRAFs.
@en
type
label
CD40 signaling through tumor n ...... am pathways by distinct TRAFs.
@en
prefLabel
CD40 signaling through tumor n ...... am pathways by distinct TRAFs.
@en
P2093
P2860
P356
P1476
CD40 signaling through tumor n ...... am pathways by distinct TRAFs.
@en
P2093
P2860
P304
14246-14254
P356
10.1074/JBC.274.20.14246
P407
P577
1999-05-01T00:00:00Z