Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.
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The Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) - Mechanisms and OpportunitiesTransient Abnormal Myelopoiesis and AML in Down Syndrome: an UpdateThe NF1 somatic mutational landscape in sporadic human cancers.The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse modelClonal evolution in myelodysplastic syndromesHistone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis.Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiencyComparison of microRNA expression profiles in K562-cells-derived microvesicles and parental cells, and analysis of their roles in leukemia.MEK1 is required for the development of NRAS-driven leukemia.RAS MAPK inhibitors deregulation in leukemiaTurning the tide in myelodysplastic/myeloproliferative neoplasms.Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34(+) cells of juvenile myelomonocytic leukemia.MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatmentGenotype and phenotype spectrum of NRAS germline variants.Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group.RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.The genomic landscape of pediatric myelodysplastic syndromes.Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia.Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.Yolk sac erythromyeloid progenitors expressing gain of function PTPN11 have functional features of JMML but are not sufficient to cause disease in mice.Recurrently affected genes in juvenile myelomonocytic leukaemia.Novel approaches to diagnosis and treatment of Juvenile Myelomonocytic Leukemia.Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.Downregulation of ROS1 enhances the therapeutic efficacy of arsenic trioxide in acute myeloid leukemia cell lines.Diagnosis and treatment of juvenile myelomonocytic leukemia.Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice.
P2860
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P2860
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Juvenile myelomonocytic leukem ...... pathway and the PRC2 network.
@en
type
label
Juvenile myelomonocytic leukem ...... pathway and the PRC2 network.
@en
prefLabel
Juvenile myelomonocytic leukem ...... pathway and the PRC2 network.
@en
P2093
P50
P356
P1433
P1476
Juvenile myelomonocytic leukem ...... S pathway and the PRC2 network
@en
P2093
André Baruchel
Audrey Contet
Aurélie Caye
Capucine Picard
Catherine Paillard
Claire Galambrun
Dalila Adjaoud
Dieter Häussinger
Dominique Vidaud
Elodie Lainey
P2888
P304
P356
10.1038/NG.3420
P407
P50
P577
2015-10-12T00:00:00Z
P5875
P6179
1003924954