Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.
about
Optimization of triazine nitriles as rhodesain inhibitors: structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal structure analysis with human cathepsin LMining a cathepsin inhibitor library for new antiparasitic drug leadsAgrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas diseaseIdentification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPBResistance of Entamoeba histolytica to the cysteine proteinase inhibitor E64 is associated with secretion of pro-enzymes and reduced pathogenicity.RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model.Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cellsGlycosylphosphatidylinositol-dependent protein trafficking in bloodstream stage Trypanosoma brucei.Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease.The cysteine proteinase inhibitor Z-Phe-Ala-CHN2 alters cell morphology and cell division activity of Trypanosoma brucei bloodstream forms in vivo.Novel antitrypanosomal agents.A parasite cysteine protease is key to host protein degradation and iron acquisition.Structure-guided development of selective TbcatB inhibitorsMolecular recognition in chemical and biological systems.Nicotinamide inhibits the lysosomal cathepsin b-like protease and kills African trypanosomes.A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei.Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatBα-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB.The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F.Role of the Trypanosoma brucei natural cysteine peptidase inhibitor ICP in differentiation and virulence.Peptidyl diazomethyl ketones inhibit the human rhinovirus 3C protease: effect on virus yield by partial block of P3 polyprotein processing.Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent.Cysteine protease inhibitors as potential antiparasitic agentsCysteine proteases in protozoan parasitesTrypanocidal and cysteine protease inhibitory activity of isopentyl caffeate is not linked in Trypanosoma bruceiProteases ofTrypanosoma brucei
P2860
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P2860
Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Trypanosoma brucei: killing of ...... nase inhibitor Z-phe-ala-CHN2.
@en
type
label
Trypanosoma brucei: killing of ...... nase inhibitor Z-phe-ala-CHN2.
@en
prefLabel
Trypanosoma brucei: killing of ...... nase inhibitor Z-phe-ala-CHN2.
@en
P2093
P356
P1476
Trypanosoma brucei: killing of ...... nase inhibitor Z-phe-ala-CHN2.
@en
P2093
P304
P356
10.1006/EXPR.1998.4381
P577
1999-04-01T00:00:00Z