Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
about
Crystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma bruceiCure of hookworm infection with a cysteine protease inhibitorAssessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.Synthesis and biochemical evaluation of thiochromanone thiosemicarbazone analogues as inhibitors of cathepsin L.The marine sponge Diacarnus bismarckensis as a source of peroxiterpene inhibitors of Trypanosoma brucei, the causative agent of sleeping sickness.Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin.Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L.Structure-guided development of selective TbcatB inhibitorsTrypanocidal drugs: mechanisms, resistance and new targets.State of the art in African trypanosome drug discovery.Drug discovery and human African trypanosomiasis: a disease less neglected?Visible Light Photoredox Cross-Coupling of Acyl Chlorides with Potassium Alkoxymethyltrifluoroborates: Synthesis of α-Alkoxyketones.Antimalarial activity of thiosemicarbazones and purine derived nitriles.
P2860
Q27662211-50B2D337-6CEC-42C2-96F6-890489C67E1EQ28480978-5F07163A-7C28-4BDD-999D-A23EDF7E2942Q33543529-FACCE405-E3C5-4CA4-A242-5697093C8CC7Q33630596-9D6C6A63-459C-4FC6-9A73-D8D611AF8ACDQ33893778-07264E0B-E63C-40B5-8A31-9133C0257D6DQ34363517-3C1B3B43-F2D9-4E45-84DE-3E3CACE7F3C6Q35385420-695993D6-086A-467C-A63C-2DE9B2E25809Q36775345-78974CA4-CB0C-4450-94B6-FEF879EC6C2FQ37388725-4092EAC6-9CF3-4481-8B9F-7DDE04F8AE05Q37623081-F5920151-8690-4AE7-8C9B-77AF8BD340DCQ37852737-03DAE181-4E05-4EE7-900C-5D08FF8F1C7BQ38154344-2C291FBB-24C1-407E-8CBD-05DB2D9DFF06Q41878035-724DFE30-1259-4E21-B0C1-845E79EF0027Q41938383-C2F44D38-F1F2-45DD-9F75-5B64585EF4E8
P2860
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
@en
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.
@nl
type
label
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
@en
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.
@nl
prefLabel
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
@en
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.
@nl
P2093
P2860
P1476
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
@en
P2093
Aaron Kosinski
Anang Shelat
Conor R Caffrey
Fangyi Zhu
Jeremy P Mallari
Michele Connelly
P2860
P304
P356
10.1016/J.BMCL.2008.03.083
P407
P577
2008-04-08T00:00:00Z