LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.
about
Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptidesMolecular Selection, Modification and Development of Therapeutic Oligonucleotide AptamersNMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamerEssential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat proteinMolecular beacons of xeno-nucleic acid for detecting nucleic acidAptamers and the next generation of diagnostic reagents.Synthetic genetic polymers capable of heredity and evolution.Miravirsen (SPC3649) can inhibit the biogenesis of miR-122.Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA LoopDNA mimics for the rapid identification of microorganisms by fluorescence in situ hybridization (FISH).Application of locked nucleic acids to improve aptamer in vivo stability and targeting functionLocked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals.Delivery systems for in vivo use of nucleic Acid drugs.Applications of peptide nucleic acids (PNAs) and locked nucleic acids (LNAs) in biosensor development.Characterisation of aptamers for therapeutic studies.Aptamers as imaging agents.In vitro selection of BNA (LNA) aptamers.Steric block high affinity oligonucleotide analogues: a new tool for mapping RNA-protein binding sites.Aptamers against pathogenic microorganisms.Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides.Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes.A chemical synthesis of LNA-2,6-diaminopurine riboside, and the influence of 2'-O-methyl-2,6-diaminopurine and LNA-2,6-diaminopurine ribosides on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexes.Ion trap collision-induced dissociation of locked nucleic acids.Aptamers Selected for Recognizing Amyloid β-Protein-A Case for Cautious Optimism.Locked Nucleic Acid Oligonucleotides toward Clinical Applications
P2860
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P2860
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.
description
2004 nî lūn-bûn
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2004年の論文
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name
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.
@en
type
label
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.
@en
prefLabel
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.
@en
P2093
P2860
P356
P1476
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1
@en
P2093
Carmelo Di Primo
Henrik Orum
Jens Bo Hansen
P2860
P304
P356
10.1093/NAR/GKH636
P577
2004-06-04T00:00:00Z