No role for pepstatin-A-sensitive acidic proteinases in reovirus infections of L or MDCK cells.
about
Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells.Transport to late endosomes is required for efficient reovirus infectionSimilar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin-Darby canine kidney cells.Mutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly.Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.Antitumor activity of ribonuclease multimers created by site-specific covalent tethering.A single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structure.Thermolabilizing pseudoreversions in reovirus outer-capsid protein micro 1 rescue the entry defect conferred by a thermostabilizing mutation.Fluorogenic label to quantify the cytosolic delivery of macromolecules.Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity.Reovirus virion-like particles obtained by recoating infectious subvirion particles with baculovirus-expressed sigma3 protein: an approach for analyzing sigma3 functions during virus entry.In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3.Sites and determinants of early cleavages in the proteolytic processing pathway of reovirus surface protein sigma3.Strategy for nonenveloped virus entry: a hydrophobic conformer of the reovirus membrane penetration protein micro 1 mediates membrane disruption.Cathepsin S supports acid-independent infection by some reoviruses.Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells.Secretory ribonucleases are internalized by a dynamin-independent endocytic pathwayPolyarginine as a multifunctional fusion tag.KFERQ sequence in ribonuclease A-mediated cytotoxicity.
P2860
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P2860
No role for pepstatin-A-sensitive acidic proteinases in reovirus infections of L or MDCK cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
No role for pepstatin-A-sensit ...... infections of L or MDCK cells.
@en
type
label
No role for pepstatin-A-sensit ...... infections of L or MDCK cells.
@en
prefLabel
No role for pepstatin-A-sensit ...... infections of L or MDCK cells.
@en
P2093
P356
P1433
P1476
No role for pepstatin-A-sensit ...... infections of L or MDCK cells.
@en
P2093
Kothandaraman S
P304
P356
10.1006/VIRO.1998.9434
P407
P577
1998-11-01T00:00:00Z