Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.
about
Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells.Diminished reovirus capsid stability alters disease pathogenesis and littermate transmissionTransport to late endosomes is required for efficient reovirus infectionA monoclonal antibody specific for reovirus outer-capsid protein sigma3 inhibits sigma1-mediated hemagglutination by steric hindrance.Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3.A single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structure.Reovirus cell entry requires functional microtubules.Molecular determinants of proteolytic disassembly of the reovirus outer capsid.From touchdown to transcription: the reovirus cell entry pathwayReovirus receptors, cell entry, and proapoptotic signaling.Sites and determinants of early cleavages in the proteolytic processing pathway of reovirus surface protein sigma3.Cathepsin S supports acid-independent infection by some reoviruses.Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells.A plasmid-based reverse genetics system for animal double-stranded RNA viruses.
P2860
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P2860
Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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name
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@ast
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@en
type
label
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@ast
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@en
prefLabel
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@ast
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@en
P2093
P2860
P1433
P1476
Adaptation of reovirus to grow ...... l outer-capsid protein sigma3.
@en
P2093
D E Brumbaugh
J D Wetzel
L E Stobie
S R Chance
T S Dermody
P2860
P304
P356
10.1128/JVI.75.7.3197-3206.2001
P577
2001-04-01T00:00:00Z