Controlling IGF-receptor function: a possible strategy for tumor therapy.
about
Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificityCrystal structure of the first three domains of the type-1 insulin-like growth factor receptorSmall interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer modelInsulin-like growth factor I receptor signaling in transformation by src oncogenes.IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.Apicidin-resistant HA22T hepatocellular carcinoma cells strongly activated the Wnt/β-catenin signaling pathway and MMP-2 expression via the IGF-IR/PI3K/Akt signaling pathway enhancing cell metastatic effect.Apicidin-resistant HA22T hepatocellular carcinoma cells massively promote pro-survival capability via IGF-IR/PI3K/Akt signaling pathway activation.Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.The IGF-I receptor and cancer.miR-143 inhibits bladder cancer cell proliferation and enhances their sensitivity to gemcitabine by repressing IGF-1R signaling.Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.Cyproterone, norethindrone, medroxyprogesterone and levonorgestrel are less potent local human growth hormone and insulin-like growth factor I secretion stimulators than progesterone in human breast cancer explants expressing the estrogen receptor.Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
P2860
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P2860
Controlling IGF-receptor function: a possible strategy for tumor therapy.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Controlling IGF-receptor function: a possible strategy for tumor therapy.
@en
type
label
Controlling IGF-receptor function: a possible strategy for tumor therapy.
@en
prefLabel
Controlling IGF-receptor function: a possible strategy for tumor therapy.
@en
P1476
Controlling IGF-receptor function: a possible strategy for tumor therapy.
@en
P2093
P304
P356
10.1016/0167-7799(96)10023-8
P577
1996-05-01T00:00:00Z