The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc.

The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc.

Item
http://www.wikidata.org/entity/Q40998639
Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activationNew role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathwayShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms.Adapter protein Shc regulates Janus kinase 3 phosphorylationDisruption of the Shc/Grb2 complex during abelson virus transformation affects proliferation, but not apoptosis.Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell deathAbrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice.Interleukin-15 regulates proliferation and self-renewal of adult neural stem cellsActivation of mitogen-activated protein kinase kinase (MEK)/extracellular signal regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment.Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cellsPrevention of lymphocyte cell death in sepsis improves survival in mice.Interleukin-2-independent proliferation of human melanoma-reactive T lymphocytes transduced with an exogenous IL-2 gene is stimulation dependentUpdate on use of aldesleukin for treatment of high-risk metastatic melanoma.Differential regulation of the IL-17 receptor by gammac cytokines: inhibitory signaling by the phosphatidylinositol 3-kinase pathway.p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.
P2860

The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc.

Item
http://www.wikidata.org/entity/Q40998639
description
1998 nî lūn-bûn
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1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The IL-2 receptor promotes pro ...... ough the adapter molecule Shc.
@en
type
label
The IL-2 receptor promotes pro ...... ough the adapter molecule Shc.
@en
prefLabel
The IL-2 receptor promotes pro ...... ough the adapter molecule Shc.
@en
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P1433
P1476
The IL-2 receptor promotes pro ...... ough the adapter molecule Shc.
@en
P2093
P304
P31
P407
P433
P478
P577
P698