3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins.
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Role of HMG-CoA Reductase Inhibitors in Neurological DisordersDiverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cellsPleiotropic effects of statinsAre statins anti-inflammatory?HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statinsPravastatin suppresses the interleukin-8 production induced by thrombin in human aortic endothelial cells cultured with high glucose by inhibiting the p44/42 mitogen activated protein kinaseStatin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-IDynamic partitioning of a glycosyl-phosphatidylinositol-anchored protein in glycosphingolipid-rich microdomains imaged by single-quantum dot tracking.Chemoprevention of melanoma.Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells.Salvaging the zone of stasis by simvastatin: an experimental study in rats.Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study.Statins induce hypothrombotic states?Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytesStatins and cardiovascular diseases: from cholesterol lowering to pleiotropyPPAR agonists as direct modulators of the vessel wall in cardiovascular disease.Do pleiotropic effects of statins beyond lipid alterations exist in vivo? What are they and how do they differ between statins?Radiation as a risk factor for cardiovascular disease.Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke.Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.Statins: mechanism of action and effects.Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin.Isoprenoids as mediators of the biological effects of statinsVascular pleiotropy of statins: clinical evidence and biochemical mechanisms.Neuroprotection mediated by changes in the endothelial actin cytoskeleton.Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model.Statin use following intracerebral hemorrhage: a decision analysis.Probing antiphospholipid-mediated thrombosis: the interplay between anticardiolipin antibodies and endothelial cells.The many roles of statins in ischemic strokeIsoprenoids and related pharmacological interventions: potential application in Alzheimer's disease.3-Hydroxy-3-methylglutaryl CoA reductase inhibitors up-regulate transforming growth factor-beta signaling in cultured heart cells via inhibition of geranylgeranylation of RhoA GTPase.Survival Benefit of Statins in Hemodialysis Patients Awaiting Renal TransplantationThe effect of statin therapy in stroke outcome: a double blind clinical trial.The cellular biochemistry of cholesterol and statins: insights into the pathophysiology and therapy of Alzheimer's disease.Statins in solid organ transplantation: is there an immunosuppressive effect?Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism.Pleiotropic effects of statins: moving beyond cholesterol control.Low-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol.Statins and bone metabolism.
P2860
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P2860
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
3-Hydroxy-3-methylglutaryl coe ...... geranylation and Rho proteins.
@en
type
label
3-Hydroxy-3-methylglutaryl coe ...... geranylation and Rho proteins.
@en
prefLabel
3-Hydroxy-3-methylglutaryl coe ...... geranylation and Rho proteins.
@en
P2093
P356
P1433
P1476
3-Hydroxy-3-methylglutaryl coe ...... geranylation and Rho proteins.
@en
P2093
P304
P356
10.1161/01.RES.83.7.683
P577
1998-10-01T00:00:00Z