Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.
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Synergistic anti-leukemic interactions between ABT-199 and panobinostat in acute myeloid leukemia ex vivoInhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells.Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cellsEnhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1.N-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2.Targeting apoptosis in acute myeloid leukaemia.The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.Combined venetoclax and alvocidib in acute myeloid leukemia.Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile.
P2860
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P2860
Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Binding of Released Bim to Mcl ...... in or Cytarabine in AML Cells.
@en
type
label
Binding of Released Bim to Mcl ...... in or Cytarabine in AML Cells.
@en
prefLabel
Binding of Released Bim to Mcl ...... in or Cytarabine in AML Cells.
@en
P2093
P2860
P1476
Binding of Released Bim to Mcl ...... cin or Cytarabine in AML Cells
@en
P2093
Chengzhi Xie
Holly Edwards
J Timothy Caldwell
Jeffrey W Taub
Jianyun Zhao
Roland Chu
Xiaohong Zhang
P2860
P304
P356
10.1158/1078-0432.CCR-15-3057
P407
P577
2016-04-21T00:00:00Z