Dominant-negative c-Jun NH2-terminal kinase 2 sensitizes renal inner medullary collecting duct cells to hypertonicity-induced lethality independent of organic osmolyte transport.
about
Multiple kinase cascades mediate prolactin signals to activating protein-1 in breast cancer cellsKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationRole of AQP2 during apoptosis in cortical collecting duct cellsStress- and cell type-dependent regulation of transfected c-Jun N-terminal kinase and mitogen-activated protein kinase kinase isoformsIn vivo regulation of MAP kinases in Ratus norvegicus renal papilla by water loading and restrictionIdentification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.Signalling and gene regulation by urea and NaCl in the renal medulla.Osmoregulation in the mammalian kidney: the role of organic osmolytes.The signals of FGFs on the neurogenesis of embryonic stem cellsThe expression of the gamma subunit of Na-K-ATPase is regulated by osmolality via C-terminal Jun kinase and phosphatidylinositol 3-kinase-dependent mechanisms.The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells.MAPK signaling and the kidney.Activation of c-Jun NH2-terminal kinase is required for gemcitabine's cytotoxic effect in human lung cancer H1299 cells.Chloride, not sodium, stimulates expression of the gamma subunit of Na/K-ATPase and activates JNK in response to hypertonicity in mouse IMCD3 cellsMAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals.p38 MAP kinase modulates liver cell volume through inhibition of membrane Na+ permeability.JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase.Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex.Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.How do kidney cells adapt to survive in hypertonic inner medulla?Multiple cell death pathways are independently activated by lethal hypertonicity in renal epithelial cells.c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun.The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia.Silencing and overexpression of the gamma-subunit of Na-K-ATPase directly affect survival of IMCD3 cells in response to hypertonic stress.Synthesis of the Na-K-ATPase gamma-subunit is regulated at both the transcriptional and translational levels in IMCD3 cells.Osmotic diuretics induce adenosine A1 receptor expression and protect renal proximal tubular epithelial cells against cisplatin-mediated apoptosis.Long-term adaptation of renal cells to hypertonicity: role of MAP kinases and Na-K-ATPase.MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells.Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium.The osmoregulatory and the amino acid-regulated responses of system A are mediated by different signal transduction pathways.Hypotonicity reduces the activity of murine aquaporin-2 promoter induced by dibutyryl cAMP.Urea inhibits hypertonicity-inducible TonEBP expression and action.Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin.
P2860
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P2860
Dominant-negative c-Jun NH2-terminal kinase 2 sensitizes renal inner medullary collecting duct cells to hypertonicity-induced lethality independent of organic osmolyte transport.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Dominant-negative c-Jun NH2-te ...... of organic osmolyte transport.
@en
type
label
Dominant-negative c-Jun NH2-te ...... of organic osmolyte transport.
@en
prefLabel
Dominant-negative c-Jun NH2-te ...... of organic osmolyte transport.
@en
P2093
P2860
P356
P1476
Dominant-negative c-Jun NH2-te ...... of organic osmolyte transport.
@en
P2093
Heasley LE
Siriwardana G
Wojtaszek PA
P2860
P304
P356
10.1074/JBC.273.2.800
P407
P577
1998-01-01T00:00:00Z