Negative cooperativity in the human bradykinin B2 receptor.
about
Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.Kinins, receptors, kininases and inhibitors--where did they lead us?Modeling the role of negative cooperativity in metabolic regulation and homeostasisPharmacological characterization of the bradykinin B2 receptor: inter-species variability and dissociation between binding and functional responsesRadioligand dissociation measurements: potential interference of rebinding and allosteric mechanisms and physiological relevance of the biological model systems.Bradykinin-induced internalization of the human B2 receptor requires phosphorylation of three serine and two threonine residues at its carboxyl tail.Inhibition of sequestration of human B2 bradykinin receptor by phenylarsine oxide or sucrose allows determination of a receptor affinity shift and ligand dissociation in intact cells.Expression levels strongly affect ligand-induced sequestration of B2 bradykinin receptors in transfected cells.Activation of mitogen-activated protein kinase by the bradykinin B2 receptor is independent of receptor phosphorylation and phosphorylation-triggered internalization.Agonist stimulation of B1 and B2 kinin receptors causes activation of the MAP kinase signaling pathway, resulting in the translocation of AP-1 in HEK 293 cells.Requirement for direct cross-talk between B1 and B2 kinin receptors for the proliferation of androgen-insensitive prostate cancer PC3 cells.Dissimilar mechanisms of Ca(2+) response to bradykinin in different types of juxtamedullary glomerular arterioles.Negative cooperativity of glutamate binding in the dimeric metabotropic glutamate receptor subtype 1.Effects of N-, P/Q- and L-type calcium channel blockers on nociceptive neurones of the trigeminal nucleus with input from the dura.
P2860
Q33257856-33FABD4C-BE2E-4A37-B043-A41745F5C63DQ34189945-5C18FBD8-00BD-43BD-B3E4-3A80228FF84EQ34477552-40BF5AC0-EEEA-4FF9-9C4E-893927938BBAQ35028551-280C38E1-2763-4245-9245-B82B6CA4FD33Q38014940-555128E3-BF9B-47AC-8BFE-7EA21C12D86FQ38325673-7470F249-224D-48B8-9012-57F6802ADF07Q38335243-9F1BF132-FD55-4836-B53F-1060E40DA85CQ40648440-F03C421A-4429-431D-8D37-D53DC57E0B87Q40947833-426A77DE-12D1-4AB3-9B70-25CC969EC1C1Q41005716-89AF9263-F930-4F69-99E9-071A3D029071Q41807720-524A1AFC-4BDC-4F2C-8A64-9F1CA5269FCBQ42479952-6DC5D014-A211-42E6-AA91-C3369B4473E8Q44938121-E04D48D6-00A3-4DF6-BDAA-99BD7B04B612Q47927136-A2EA0D07-48CA-4087-9BAB-F64D7E044783
P2860
Negative cooperativity in the human bradykinin B2 receptor.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Negative cooperativity in the human bradykinin B2 receptor.
@en
type
label
Negative cooperativity in the human bradykinin B2 receptor.
@en
prefLabel
Negative cooperativity in the human bradykinin B2 receptor.
@en
P2093
P2860
P356
P1476
Negative cooperativity in the human bradykinin B2 receptor
@en
P2093
F Alhenc-Gelas
J Allegrini
J Marchetti
R M Rajerison
P2860
P304
P356
10.1074/JBC.273.3.1309
P407
P50
P577
1998-01-01T00:00:00Z