The molecular response of mammalian cells to hypoxia and the potential for exploitation in cancer therapy.
about
The radiomimetic enediyne, 20'-deschloro-C-1027 induces inter-strand DNA crosslinks in hypoxic cells and overcomes cytotoxic radioresistanceHypoxia-inducible regulation of a prodrug-activating enzyme for tumor-specific gene therapy.Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix.Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast.Proportion of infiltrating IgG-binding immune cells predict for tumour hypoxia.Relationship of hypoxia to metastatic ability in rodent tumoursHypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis.C-1027, a radiomimetic enediyne anticancer drug, preferentially targets hypoxic cellsNF-kappaB inhibition impairs the radioresponse of hypoxic EMT-6 tumour cells through downregulation of inducible nitric oxide synthase.Energy metabolism in human melanoma cells under hypoxic and acidic conditions in vitro.Chronic hypoxia modulates tumour cell radioresponse through cytokine-inducible nitric oxide synthase.
P2860
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P2860
The molecular response of mammalian cells to hypoxia and the potential for exploitation in cancer therapy.
description
1996 nî lūn-bûn
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1996年の論文
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1996年学术文章
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1996年学术文章
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1996年学术文章
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1996年学术文章
@zh-my
1996年学术文章
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1996年學術文章
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1996年學術文章
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1996年學術文章
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name
The molecular response of mamm ...... xploitation in cancer therapy.
@en
type
label
The molecular response of mamm ...... xploitation in cancer therapy.
@en
prefLabel
The molecular response of mamm ...... xploitation in cancer therapy.
@en
P2860
P1476
The molecular response of mamm ...... xploitation in cancer therapy.
@en
P2093
I J Stratford
P2860
P304
P577
1996-07-01T00:00:00Z