Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming protein.
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The BPV-1 E5 protein, the 16 kDa membrane pore-forming protein and the PDGF receptor exist in a complex that is dependent on hydrophobic transmembrane interactionsReplacement of interleukin-2 (IL-2)-generated mitogenic signals by a mink cell focus-forming (MCF) or xenotropic virus-induced IL-9-dependent autocrine loop: implications for MCF virus-induced leukemogenesisThe cellular response to neuregulins is governed by complex interactions of the erbB receptor familyPacking contacts can mediate highly specific interactions between artificial transmembrane proteins and the PDGFbeta receptor.Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor.Bovine papillomavirus E5 protein induces oligomerization and trans-phosphorylation of the platelet-derived growth factor beta receptor.The bovine papillomavirus E5 protein requires a juxtamembrane negative charge for activation of the platelet-derived growth factor beta receptor and transformation of C127 cells.Construction and maintenance of randomized retroviral expression libraries for transmembrane protein engineering.Upregulation of tyrosine kinase TKT by the Epstein-Barr virus transactivator ZtaCooperative transformation and coexpression of bovine papillomavirus type 1 E5 and E7 proteinsStructural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5.Human papillomaviruses and the interferon responseProductive infection of bovine papillomavirus type 2 in the placenta of pregnant cows affected with urinary bladder tumorsBiology of human papillomaviruses.Plakophilin-2 promotes activation of epidermal growth factor receptor.The E5 proteinsQuantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle.Multiple transmembrane amino acid requirements suggest a highly specific interaction between the bovine papillomavirus E5 oncoprotein and the platelet-derived growth factor beta receptor.Viral miniproteinsCellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein.Papillomavirus E5: the smallest oncoprotein with many functions.Biologically active LIL proteins built with minimal chemical diversity.Mutational analysis of the interaction between the bovine papillomavirus E5 transforming protein and the endogenous beta receptor for platelet-derived growth factor in mouse C127 cells.Mutational analysis of the beta-type platelet-derived growth factor receptor defines the site of interaction with the bovine papillomavirus type 1 E5 transforming protein.Effect of human papillomavirus type 16 oncogenes on MAP kinase activity.Human adenovirus type 9 E4 open reading frame 1 encodes a cytoplasmic transforming protein capable of increasing the oncogenicity of CREF cellsE5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation.Mutational analysis of human papillomavirus type 11 E5a oncoproteinThe human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surfaceIdentification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein.A carboxy-terminal region required by the adenovirus type 9 E4 ORF1 oncoprotein for transformation mediates direct binding to cellular polypeptides.Bovine papillomavirus E7 oncoprotein inhibits anoikis.Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.Structurally related class I and class II receptor protein tyrosine kinases are down-regulated by the same E3 protein coded for by human group C adenovirusesThe v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein.Human papillomavirus type 16 E5 protein as a therapeutic target.Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.The bovine papillomavirus type 1 E5 transforming protein specifically binds and activates the beta-type receptor for the platelet-derived growth factor but not other related tyrosine kinase-containing receptors to induce cellular transformation.Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cells
P2860
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P2860
Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming protein.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Activation of the platelet-der ...... virus E5 transforming protein.
@en
type
label
Activation of the platelet-der ...... virus E5 transforming protein.
@en
prefLabel
Activation of the platelet-der ...... virus E5 transforming protein.
@en
P2093
P2860
P1433
P1476
Activation of the platelet-der ...... virus E5 transforming protein.
@en
P2093
P2860
P304
P407
P577
1991-04-01T00:00:00Z