STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727.
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The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayProtein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.LIF-STAT signaling and trophoblast biologyDifferential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathwaysSerine phosphorylation and negative regulation of Stat3 by JNKInvolvement of the IL-22/REG Ialpha axis in ulcerative colitisSpecificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activityRequirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.Genomic organization and regulation of the human interleukin-18 gene.Serine phosphorylation of STATs.Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformationSTAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells.STAT proteins: novel molecular targets for cancer drug discovery.Hepatitis C virus non-structural 5A abrogates signal transducer and activator of transcription-1 nuclear translocation induced by IFN-alpha through dephosphorylation.A CD4+ T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cell function.Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through α7nAChR-mediated MUC4 upregulation.Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases.Ultraviolet radiation and 12-O-tetradecanoylphorbol-13-acetate-induced interaction of mouse epidermal protein kinase Cε with Stat3 involve integration with ERK1/2.STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation.Modulation of PKCdelta signaling alters the shear stress-mediated increases in endothelial nitric oxide synthase transcription: role of STAT3.ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events.IL-2- and STAT5-regulated cytokine gene expression in cells expressing the Tax protein of HTLV-1.Angiotensin II-induced tyrosine phosphorylation of signal transducers and activators of transcription 1 is regulated by Janus-activated kinase 2 and Fyn kinases and mitogen-activated protein kinase phosphatase 1.Ataxia telangiectasia mutated proteins, MAPKs, and RSK2 are involved in the phosphorylation of STAT3.Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.Indirubin derivatives inhibit malignant lymphoid cell proliferation.Activation of insulin and IGF-1 signaling pathways by melatonin through MT1 receptor in isolated rat pancreatic islets.Herpes simplex virus remodels T-cell receptor signaling, resulting in p38-dependent selective synthesis of interleukin-10.Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression.Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cells.ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells.Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation.STAT3 is involved in phosphatidic acid-induced Bcl-2 expression in HeLa cellsThe STAT3-Ser/Hes3 signaling axis: an emerging regulator of endogenous regeneration and cancer growth.Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cellsCDK8 as the STAT1 serine 727 kinase?
P2860
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P2860
STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
STAT3 is a serine kinase targe ...... nals converge upon serine 727.
@en
type
label
STAT3 is a serine kinase targe ...... nals converge upon serine 727.
@en
prefLabel
STAT3 is a serine kinase targe ...... nals converge upon serine 727.
@en
P2860
P356
P1476
STAT3 is a serine kinase targe ...... gnals converge upon serine 727
@en
P2093
D Cantrell
P2860
P304
24542-24549
P356
10.1074/JBC.272.39.24542
P407
P50
P577
1997-09-01T00:00:00Z