Structural insights into the molecular mechanism of the m(6)A writer complex.
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The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.The m6A pathway facilitates sex determination in Drosophila.m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.Update: Mechanisms Underlying N6-Methyladenosine Modification of Eukaryotic mRNA.The Epitranscriptome of Noncoding RNAs in Cancer.A fly view on the roles and mechanisms of the m6A mRNA modification and its players.The RNA Modification N6-methyladenosine and Its Implications in Human Disease.Making the Mark: The Role of Adenosine Modifications in the Life Cycle of RNA Viruses.Dynamic RNA Modifications in Gene Expression Regulation.N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.The Dark Side of the Epitranscriptome: Chemical Modifications in Long Non-Coding RNAs.METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.The emerging role of mRNA methylation in normal and pathological behavior.Rethinking m6A Readers, Writers, and Erasers.N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications.Detection of N6-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease.Interactions, localization and phosphorylation of the m6A generating METTL3-METTL14-WTAP complex.Impact of DNA and RNA Methylation on Radiobiology and Cancer Progression.Human m6A writers: Two subunits, 2 roles.Structural insights into the RNA methyltransferase domain of METTL16.Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.The Emerging Field of Epitranscriptomics in Neurodevelopmental and Neuronal Disorders.Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism.N-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progressionN6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell FateMethylation of Structured RNA by the mA Writer METTL16 Is Essential for Mouse Embryonic DevelopmentN6-Methyladenosine Role in Acute Myeloid Leukaemia
P2860
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P2860
Structural insights into the molecular mechanism of the m(6)A writer complex.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Structural insights into the molecular mechanism of the m(6)A writer complex.
@en
type
label
Structural insights into the molecular mechanism of the m(6)A writer complex.
@en
prefLabel
Structural insights into the molecular mechanism of the m(6)A writer complex.
@en
P2860
P921
P356
P1433
P1476
Structural insights into the molecular mechanism of the m(6)A writer complex.
@en
P2093
Paweł Śledź
P2860
P356
10.7554/ELIFE.18434
P407
P577
2016-09-14T00:00:00Z