Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.

Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.

Item
http://www.wikidata.org/entity/Q41095937
Synthesis of nucleoside phosphate and phosphonate prodrugsSynthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3'-azido-2',3'-dideoxythymidinePhosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine.Synthesis and antiviral activity of aryl phosphoramidate derivatives of beta-D- and beta-L-C-5-substituted 2',3'-didehydro-2',3'-dideoxy-uridine bearing linker arms.Novel compounds in preclinical/early clinical development for the treatment of HIV infections.[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.New anti-HIV agents and targets.The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators.Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations.Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.Synthesis and evaluation of some masked phosphate esters of the anti-herpesvirus drug 882C (netivudine) as potential antiviral agents.Synthesis and anti-HIV activity of some novel chain-extended phosphoramidate derivatives of d4T (stavudine): esterase hydrolysis as a rapid predictive test for antiviral potency.Practical synthesis, separation, and stereochemical assignment of the PMPA pro-drug GS-7340.Collisionally-induced dissociation of substituted pyrimidine antiviral agents: mechanisms of ion formation using gas phase hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.AZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems.
P2860

Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.

Item
http://www.wikidata.org/entity/Q41095937
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Phosphoramidate derivatives of ...... ffect of amino acid variation.
@en
type
label
Phosphoramidate derivatives of ...... ffect of amino acid variation.
@en
prefLabel
Phosphoramidate derivatives of ...... ffect of amino acid variation.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
Phosphoramidate derivatives of ...... effect of amino acid variation
@en
P2093
P304
P31
P356
10.1016/S0166-3542(97)00029-6
P433
P478
P50
P577
P698