Cooperative binding of the Xenopus RNA polymerase I transcription factor xUBF to repetitive ribosomal gene enhancers.
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Survey and summary: transcription by RNA polymerases I and III.The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter.The role of acetylation in rDNA transcription.Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans.UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat.Nucleolar organizer regions: genomic 'dark matter' requiring illuminationRibosomal gene promoter domains can function as artificial enhancers of RNA polymerase I transcription, supporting a promoter origin for natural enhancers in Xenopus.Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).rRNA gene silencing and nucleolar dominance: insights into a chromosome-scale epigenetic on/off switchThe repeat organizer, a specialized insulator element within the intergenic spacer of the Xenopus rRNA genes.Nucleosome binding by the polymerase I transactivator upstream binding factor displaces linker histone H1.xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity.The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA.The RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acidsUBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery.The first high-mobility-group box of upstream binding factor assembles across-over DNA junction by basic residues.A Deconvolution Protocol for ChIP-Seq Reveals Analogous Enhancer Structures on the Mouse and Human Ribosomal RNA Genes.Virtually the entire Xenopus laevis rDNA multikilobase intergenic spacer serves to stimulate polymerase I transcription.
P2860
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P2860
Cooperative binding of the Xenopus RNA polymerase I transcription factor xUBF to repetitive ribosomal gene enhancers.
description
1992 nî lūn-bûn
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1992年の論文
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1992年論文
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1992年論文
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1992年論文
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1992年論文
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1992年論文
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1992年论文
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1992年论文
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1992年论文
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name
Cooperative binding of the Xen ...... tive ribosomal gene enhancers.
@en
type
label
Cooperative binding of the Xen ...... tive ribosomal gene enhancers.
@en
prefLabel
Cooperative binding of the Xen ...... tive ribosomal gene enhancers.
@en
P2860
P356
P1476
Cooperative binding of the Xen ...... tive ribosomal gene enhancers.
@en
P2093
C D Putnam
C S Pikaard
P2860
P304
P356
10.1128/MCB.12.11.4970
P407
P577
1992-11-01T00:00:00Z