Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
about
Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressantProtonated form: the potent form of potassium-competitive acid blockersSecretory state regulates Zn2+ transport in gastric parietal cell of the rabbit.A chimeric gastric H+,K+-ATPase inhibitable with both ouabain and SCH 28080.Computational insights into the interaction mechanism of triazolyl substituted tetrahydrobenzofuran derivatives with H(+),K(+)-ATPase at different pH.Mutational study on the roles of disulfide bonds in the beta-subunit of gastric H+,K+-ATPase.Alanine-scanning mutagenesis of the sixth transmembrane segment of gastric H+,K+-ATPase alpha-subunit.Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis.The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitorsDeceleration of the E1P-E2P transition and ion transport by mutation of potentially salt bridge-forming residues Lys-791 and Glu-820 in gastric H+/K+-ATPase.The negative charge of glutamic acid-820 in the gastric H+,K+-ATPase alpha-subunit is essential for K+ activation of the enzyme activity.Constitutive activation of gastric H+,K+-ATPase by a single mutationA hybrid between Na+,K+-ATPase and H+,K+-ATPase is sensitive to palytoxin, ouabain, and SCH 28080.A model of reversible inhibitors in the gastric H+/K+-ATPase binding site determined by rotational echo double resonance NMR.pH of TGN and recycling endosomes of H+/K+-ATPase-transfected HEK-293 cells: implications for pH regulation in the secretory pathway.The cavity structure for docking the K(+)-competitive inhibitors in the gastric proton pump.K binding and proton redistribution in the EP state of the H, K-ATPase
P2860
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P2860
Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
@en
type
label
Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
@en
prefLabel
Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
@en
P2093
P2860
P356
P1476
Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
@en
P2093
P2860
P304
17668-17674
P356
10.1074/JBC.272.28.17668
P407
P577
1997-07-01T00:00:00Z