Synthesis and pharmaceutical properties of N-acyloxymethyl prodrugs of Allop with potential anti-trypanosomal activity.

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Synthesis and pharmaceutical properties of N-acyloxymethyl prodrugs of Allop with potential anti-trypanosomal activity.

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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Synthesis and pharmaceutical p ...... al anti-trypanosomal activity.

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Synthesis and pharmaceutical p ...... al anti-trypanosomal activity.

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Synthesis and pharmaceutical p ...... al anti-trypanosomal activity.

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P1476

Synthesis and pharmaceutical p ...... al anti-trypanosomal activity.

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P2093

C S Ortiz

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M A Raviolo

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M S Gualdesi

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P2860

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Antitrypanosomal effect of allopurinol: conversion in vivo to aminopyrazolopyrimidine nucleotides by Trypanosoma curzi

Molecular properties that influence the oral bioavailability of drug candidates.

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host.

Physiochemical drug properties associated with in vivo toxicological outcomes.

Effect of allopurinol on Trypanosoma cruzi: metabolism and biological activity in intracellular and bloodstream forms.

Drug permeation in biomembranes: in vitro and in silico prediction and influence of physicochemical properties.

Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study.

Chagas disease: progress and new perspectives.

Potential new clinical therapies for Chagas disease.

P304

602-610

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P31

scholarly article

P356

10.3109/03639045.2015.1061539

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P407

English

P433

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P478

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P577

2015-07-16T00:00:00Z

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P698

26181622

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