Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events.
about
The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferationThe N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosomeA cell signal pathway involving laminin-5, alpha3beta1 integrin, and mitogen-activated protein kinase can regulate epithelial cell proliferationThe beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assemblyBinding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament bindingHemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180The localization of bullous pemphigoid antigen 180 (BP180) in hemidesmosomes is mediated by its cytoplasmic domain and seems to be regulated by the beta4 integrin subunitPancreatic cancer stem cell markers and exosomes - the incentive pushInvestigation into the mechanism of the loss of laminin 5 (alpha3beta3gamma2) expression in prostate cancerReversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodiesTransitions in cell organization and in expression of contractile and extracellular matrix proteins during development of chicken aortic smooth muscle: evidence for a complex spatial and temporal differentiation program.FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.Laminin-5 induces osteogenic gene expression in human mesenchymal stem cells through an ERK-dependent pathway.Communication between the cell membrane and the nucleus: role of protein compartmentalization.Anchoring junctions as drug targets: role in contraceptive development.Anti-LRP/LR specific antibody IgG1-iS18 impedes adhesion and invasion of liver cancer cells.Laminin 5 in the human thymus: control of T cell proliferation via alpha6beta4 integrinsEGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion.Division of labor among the alpha6beta4 integrin, beta1 integrins, and an E3 laminin receptor to signal morphogenesis and beta-casein expression in mammary epithelial cellsLoss of alpha-dystroglycan laminin binding in epithelium-derived cancers is caused by silencing of LARGE.Cell-matrix adhesions differentially regulate fascin phosphorylation.Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.
P2860
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P2860
Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Signal transduction by the alp ...... in binding and nuclear events.
@en
type
label
Signal transduction by the alp ...... in binding and nuclear events.
@en
prefLabel
Signal transduction by the alp ...... in binding and nuclear events.
@en
P1476
Signal transduction by the alp ...... in binding and nuclear events.
@en
P2093
Giancotti FG
P304
P407
P478
109 ( Pt 6)
P577
1996-06-01T00:00:00Z